Open lung biopsy specimen showing an inflammation with thickened interalveolar septa and the inflammatory infiltration of mononuclear cells (areas of a.

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Open lung biopsy specimen showing an inflammation with thickened interalveolar septa and the inflammatory infiltration of mononuclear cells (areas of a nonspecific interstitial inflammation). Open lung biopsy specimen showing an inflammation with thickened interalveolar septa and the inflammatory infiltration of mononuclear cells (areas of a nonspecific interstitial inflammation). Areas of buds of granulation tissue and loose connective tissue in alveolar and bronchiolar lumen, gigantic cell with fissures caused by diluted cholesterol crystals (arrows) and the areas of the intra-alveolar exudates are shown. Haematoxylin and eosin stain. E. Radzikowska et al. Eur Respir J 2003;21:552-555 ©2003 by European Respiratory Society