Induction Pegylated Interferon Alfa-2b in Combination With Ribavirin in Patients With Genotypes 1 and 4 Chronic Hepatitis C: A Prospective, Randomized,

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Presentation transcript:

Induction Pegylated Interferon Alfa-2b in Combination With Ribavirin in Patients With Genotypes 1 and 4 Chronic Hepatitis C: A Prospective, Randomized, Multicenter, Open- Label Study Daniel E. Brady, Dawn M. Torres, Jong W. An, John A. Ward, Eric Lawitz, Stephen A. Harrison Clinical Gastroenterology and Hepatology Volume 8, Issue 1, Pages 66-71.e1 (January 2010) DOI: 10.1016/j.cgh.2009.08.036 Copyright © 2010 AGA Institute Terms and Conditions

Figure 1 Study schematic outlining randomization to specific study arm, dose and duration of study medication, and follow-up time interval. Clinical Gastroenterology and Hepatology 2010 8, 66-71.e1DOI: (10.1016/j.cgh.2009.08.036) Copyright © 2010 AGA Institute Terms and Conditions

Figure 2 Percentage of virus negativity seen at weeks 12, 24, 48, and 72 for each study group. Clinical Gastroenterology and Hepatology 2010 8, 66-71.e1DOI: (10.1016/j.cgh.2009.08.036) Copyright © 2010 AGA Institute Terms and Conditions

Figure 3 Weight subgroup analysis. Percentage of virus negativity at weeks 12, 24, 48, and 72 for each study group separated by weight. Clinical Gastroenterology and Hepatology 2010 8, 66-71.e1DOI: (10.1016/j.cgh.2009.08.036) Copyright © 2010 AGA Institute Terms and Conditions

Supplementary Figure 1 Consolidated Standards of Reporting Trials (CONSORT) patient flow diagram. Clinical Gastroenterology and Hepatology 2010 8, 66-71.e1DOI: (10.1016/j.cgh.2009.08.036) Copyright © 2010 AGA Institute Terms and Conditions