Omomyc-induced cytoskeletal reorganization and increased apoptosis in C2C12 cells. Omomyc-induced cytoskeletal reorganization and increased apoptosis in.

Slides:

Advertisements

Similar presentations

Cell Physiol Biochem 2014;33: DOI: /

Advertisements

Targeting the PARP DNA repair pathway enhanced cytotoxicity induced by chemotherapy. Targeting the PARP DNA repair pathway enhanced cytotoxicity induced.

DHEA(S) and Allo induced the expression of the antiapoptotic Bcl-2 proteins in serum-deprived PC12 cells. DHEA(S) and Allo induced the expression of the.

BIRC6 is expressed in the tumorigenic Aldefluorhigh fraction of colonosphere cells. BIRC6 is expressed in the tumorigenic Aldefluorhigh fraction of colonosphere.

The pathological role of Bax in cisplatin nephrotoxicity

AKT2, but not AKT1, is required for regulating survival of PTEN-deficient prostate tumor spheroids. AKT2, but not AKT1, is required for regulating survival.

Volume 54, Issue 4, Pages (October 1998)

Fig. 1. Effects on the tight junction barrier and permeability following doxorubicin and Herceptin treatment. Effects on the tight junction barrier and.

MiR-200c/141 overexpression in LS-8 cells induces E-cad expression and cell-cell adhesion. miR-200c/141 overexpression in LS-8 cells induces E-cad expression.

USP2a regulates MYC expression through the MDM2–p53 axis.

Cdc2 expression in cultured Schwann cells.

SW fraction induces S phase arrest and apoptosis.

Integrin β3 is dispensable for RhoA activity and contractility.

CYP1A1 knockdown increases cell death.

BEZ235 induces MAPK signaling in a FOXO3A-dependent manner.

Aplf downregulation does not induce cellular arrest.

Apoptosis in CAM vessels after staining with TUNEL

IKKβ protects adipocytes from HFD-induced cell death.

BCX inhibits lamellipodia formation in lung cells.

DHA induces apoptosis independently from caspase-8 and FADD in Jurkat T-lymphoma cells. DHA induces apoptosis independently from caspase-8 and FADD in.

Streptavidin identified in the vaccine protein profiles.

CDCP1 is required for invadopodia formation and ECM degradation by human breast cancer cells. CDCP1 is required for invadopodia formation and ECM degradation.

Mapping the Pirh2 and p73 interaction sites.

ALDH1A3 is mainly responsible for the ALDH activity in two human cholangiocarcinoma lines. ALDH1A3 is mainly responsible for the ALDH activity in two human.

Mitotic catastrophe symptoms caused by curcumin are followed by apoptosis. Mitotic catastrophe symptoms caused by curcumin are followed by apoptosis. A.

Expression of versican in mammary tumor stem/progenitor cells.

Quercetin induces apoptosis in P39 xenografts.

Depletion of HDAC2 sensitizes cells to epirubicin-induced apoptosis.

Greater induction of apoptosis following EGFR TKI treatment correlates with higher basal BIM expression across a panel of EGFR-mutant lung cancers. Greater.

CXCR4 expression levels of MDA-MB-231 cells at 48 hours posttransfection of CXCR4 siRNAs. CXCR4 expression levels of MDA-MB-231 cells at 48 hours posttransfection.

Ectopic expression of miR-187 in MCF7 cells results in increased migration, invasion, and anchorage-independent colony formation. Ectopic expression of.

Expression of CRC stem cell markers and L1 in CRC cells.

Effect of SFN on the protein expression of Nrf2, HO-1, and NQO1 in JB6-shMock and JB6-shNrf2 cells. Effect of SFN on the protein expression of Nrf2, HO-1,

Biological effects of BRAF silencing: growth curves of A375 (A) and ARO (B) cell lines in the absence or presence of doxycycline. Biological effects of.

N-3 PUFAs promote endometrial cancer cell apoptosis in vitro and in vivo. n-3 PUFAs promote endometrial cancer cell apoptosis in vitro and in vivo. HEC-1-A.

T-cell activation and induction of apoptosis in epithelial cells of oral lesions induced by 4-NQO. T-cell activation and induction of apoptosis in epithelial.

KPT-9274 shows specificity for attenuation of PAK4 targets preferentially in RCC cells. KPT-9274 shows specificity for attenuation of PAK4 targets preferentially.

Effect of GSK3β inhibition on cell survival and proliferation of glioblastoma cells. Effect of GSK3β inhibition on cell survival and proliferation of glioblastoma.

Effect of coapplication of dexrazoxane and doxorubicin on DSB formation, TOP2A protein level, and apoptosis. Effect of coapplication of dexrazoxane and.

Per1 inhibits growth and induces apoptosis in prostate cancer cell lines. Per1 inhibits growth and induces apoptosis in prostate cancer cell lines. LNCaP,

COX-2, Oct-4, and ALDH-1 expression in the mammary gland.

Induction of apoptosis in mismatch repair-deficient tumor cell lines after microinjection of phMSH2 and phMLH1 cDNA expression constructs. Induction of.

SBC-5 miR-335+, but not SBC-5 miR-29a+, exhibited reduced IGF-IR expression. SBC-5 miR-335+, but not SBC-5 miR-29a+, exhibited reduced IGF-IR expression.

Cellular localization of Panx1 and altered membrane morphology in stable Panx1-transfected C6 glioma cells. Cellular localization of Panx1 and altered.

BCG uptake by bladder cancer cells requires activated Pak1.

IGF-I partially protects Rh30 cells from apoptosis despite simultaneous inhibition of PI3K-Akt and MAP kinase pathways. IGF-I partially protects Rh30 cells.

Met is expressed in Her2-overexpressing cell lines and Her2 (+) breast tumors. Met is expressed in Her2-overexpressing cell lines and Her2 (+) breast tumors.

WP1066 induces caspase-dependent apoptosis.

C-MYC overexpression or growth in serum-containing media induces EMT in HBEC3p53,KRAS. c-MYC overexpression or growth in serum-containing media induces.

The combination of trastuzumab and SU11274 abrogate Akt phosphorylation. The combination of trastuzumab and SU11274 abrogate Akt phosphorylation. Serum-starved.

Expression of PCNA, K10, and K5 in skin lesions from Stat3+/−:HPV8 and Stat3+/+:HPV8 mice. Expression of PCNA, K10, and K5 in skin lesions from Stat3+/−:HPV8.

Effect of SPINDLIN1 protein on cancer cell proliferation and invasion.

Induction of apoptosis by statins in NB4 cells and NB4 variant cell lines. Induction of apoptosis by statins in NB4 cells and NB4 variant cell lines. A,

Enhanced expression of Cap43 gene by nickel in breast cancer cell lines. Enhanced expression of Cap43 gene by nickel in breast cancer cell lines. Expression.

Purified Vpr induces double-strand breaks in vitro.

AS1411 alters subcellular distribution of PRMT5 in a time-dependent, dose-dependent, and nucleolin-dependent manner. AS1411 alters subcellular distribution.

CHL-induced apoptosis in HCT116 cells involves the activation of procaspase-8 and procaspase-6, with cleavage of nuclear lamins. CHL-induced apoptosis.

SAHA blocks IR-induced increase of RAD51 protein in MM cells.

Effect of bevacizumab on the proliferation of A2780 cells.

Immune response of CEA-transgenic mice transferred with OT-1 splenocytes and immunized with ovalbumin and adjuvant. Immune response of CEA-transgenic mice.

Flavopiridol inhibits rhabdoid cell survival and induces cell cycle arrest and apoptosis. Flavopiridol inhibits rhabdoid cell survival and induces cell.

W. chinensis extract induces apoptosis in AR-dependent prostate cancer cells. W. chinensis extract induces apoptosis in AR-dependent prostate cancer cells.

RA-9 induces G2–M cell-cycle arrest and caspase-mediated apoptosis in ovarian cancer cells. RA-9 induces G2–M cell-cycle arrest and caspase-mediated apoptosis.

Effect of BCAA on the progression of cell cycle, expression of p21CIP1, and induction of apoptosis in HepG2 cells in the presence and absence of visfatin.

Leukocyte populations in normal and neoplastic breast tissues.

Effect of SFN on the total activity and protein expression of HDACs in JB6 P+ cells. Effect of SFN on the total activity and protein expression of HDACs.

T3 or T4 induces MAPK activation in myeloma cells.

Knockdown of NR4A1 induces endoplasmic reticulum stress–mediated apoptosis by increasing ROS production in pancreatic cancer cells. Knockdown of NR4A1.

Effect of 6-SHO on mouse prostate cancer HMVP2 cells.

Determination of Per2 (left), MTNR1A (middle), and ERβ (right) protein expression levels in mammary tissues of rats sacrificed at ZT12. Determination of.

Presentation transcript:

Omomyc-induced cytoskeletal reorganization and increased apoptosis in C2C12 cells. Omomyc-induced cytoskeletal reorganization and increased apoptosis in C2C12 cells. A, omomer expression (Western blot) in C2C12 cells harboring control (BP), Omomer, or Myc and Omomer retroviruses (Myc + Omomer). B, actin fiber formation. Myc-C2C12 myoblasts harboring empty or Omomer retroviruses (Myc and Myc + Omomer, respectively) were stained with FITC-phalloidin. C, potentiation of Myc apoptosis. Myc and Myc + Omomer C2C12 cells, serum deprived and incubated with tamoxifen, were stained with Hoechst dye. Some nuclei displaying apoptotic morphological features are indicated by arrows. D, FACS analysis of serum-deprived cells. The subdiploid fraction, characteristic of apoptosis, represented 15% of the population in Myc cells and amounted to 25% in Myc + Omomer cells. Laura Soucek et al. Cancer Res 2002;62:3507-3510 ©2002 by American Association for Cancer Research