(A) Principal component analysis plot of weighted UniFrac distances of microbiota composition at baseline, week 2 and week 8 and donors. (A) Principal.

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(A) Principal component analysis plot of weighted UniFrac distances of microbiota composition at baseline, week 2 and week 8 and donors. (A) Principal component analysis plot of weighted UniFrac distances of microbiota composition at baseline, week 2 and week 8 and donors. The left panel shows METS-R and METS-D, and the right panel shows RYGB-R and RYGB-D. (B) Spider plot showing operational taxonomic unit (OTUs) of which relative change best discriminated RYGB-R subjects from METS-R subjects. (C) Spider plot of OTUs of which the relative change best discriminated RYGB-R responders from RYGB-R non-responders. (D) Spider plot of OTUs of which the relative change best discriminated METS-R deteriorators from METS-R non-deteriorators. (E) Spider plot of OTUs of which baseline abundance best discriminated responders from non-responders and (F) OTUs of which baseline abundance best discriminated deteriorators from non-deteriorators. METS-D, metabolic syndrome donors; METS-R, metabolic syndrome recipient; RYGB-D, Roux-en-Y gastric bypass donor; RYGB-R, Roux-en-Y gastric bypass recipient. Pieter de Groot et al. Gut doi:10.1136/gutjnl-2019-318320 Copyright © BMJ Publishing Group Ltd & British Society of Gastroenterology. All rights reserved.