Progastrin staining in colon adenomas and adenocarcinomas. Progastrin staining in colon adenomas and adenocarcinomas. A and B, strong staining in low-grade (A, ×20) and high-grade dysplasia adenoma (B, ×40). C–F, strong progastrin staining in adenocarcinomas at different magnifications (×4, ×20, ×40, and ×100). G, adenocarcinoma-adjacent normal tissue positive for progastrin. Antiprogastrin antibody 1137 (29) was used for all experiments. Catherine Do et al. Cancer Prev Res 2012;5:675-684 ©2012 by American Association for Cancer Research