Does eczema in infancy cause hay fever, asthma, or both in childhood

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Presentation transcript:

Does eczema in infancy cause hay fever, asthma, or both in childhood Does eczema in infancy cause hay fever, asthma, or both in childhood? Insights from a novel regression model of sibling data John L. Hopper, BSc, MSc, PhD, BA, Quang M. Bui, BSc (Hons), PhD, Bircan Erbas, BSc, MSc, PhD, Melanie C. Matheson, BSc, MAppSc, PhD, Lyle C. Gurrin, BSc (Hons), PhD, AStat, FRSS, John A. Burgess, MBBS, FRACP, MEpid, PhD, Adrian J. Lowe, BBSc, MPH, PhD, Mark A. Jenkins, BSc (Hons), PhD, Michael J. Abramson, MBBS, BMedSc (Hons), PhD, FRACP, FAFPHM, E. Haydn Walters, BM BCh (Hons), MA, DM, FRCP, FRACP, Graham G. Giles, BSc, MSc, PhD, Shyamali C. Dharmage, MBBS, MSc, MD, PhD Journal of Allergy and Clinical Immunology Volume 130, Issue 5, Pages 1117-1122.e1 (November 2012) DOI: 10.1016/j.jaci.2012.08.003 Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Logistic regression estimates of cosibling association with infantile eczema from fitting models II and III before (shaded and unshaded bars) and after (shaded bars only) adjusting for infantile eczema of self and for having asthma and hay fever (A), hay fever only (B), and asthma only (C) in childhood before and after adjusting for parental status for the same condition. Percentage reduction after adjusting for eczema of self is shown for Fig 1, A and B. Journal of Allergy and Clinical Immunology 2012 130, 1117-1122.e1DOI: (10.1016/j.jaci.2012.08.003) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions