Whole mounts (A-D; ×20), and H&E sections (E-H, ×100) of the mammary gland. Whole mounts (A-D; ×20), and H&E sections (E-H, ×100) of the mammary gland.

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Whole mounts (A-D; ×20), and H&E sections (E-H, ×100) of the mammary gland. Whole mounts (A-D; ×20), and H&E sections (E-H, ×100) of the mammary gland. Controls (CONT) and tamoxifen-treated (TAM) animals showed normal mammary histology (A-B, E-F). Carcinogen treatment (CARC) caused preneoplasia and neoplasia (C and G), and this effect was blocked by carcinogen + tamoxifen (CARC + TAM; D and H). Secreting mammary glands were observed in CARC + TAM rats. Bar, 5 mm (A-D), 200 μm (E-H). Alison Y. Ting et al. Cancer Prev Res 2008;1:546-553 ©2008 by American Association for Cancer Research