Fig. 4 In situ extraction of cancer-related miRNAs using the nanowire-anchored microfluidic device; heat maps of the miRNA expression array for noncancer.

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Fig. 4 In situ extraction of cancer-related miRNAs using the nanowire-anchored microfluidic device; heat maps of the miRNA expression array for noncancer lung, pancreatic, liver, bladder, and prostate cancer donor urine samples (n = 3). In situ extraction of cancer-related miRNAs using the nanowire-anchored microfluidic device; heat maps of the miRNA expression array for noncancer lung, pancreatic, liver, bladder, and prostate cancer donor urine samples (n = 3). For intuitive understanding of the expression level of each miRNA and easy comparison between each group, we used color gradations showing signal intensity variation. Black, logarithmic signal intensity of 5; blue, logarithmic signal intensity less than or equal to 2; and yellow, logarithmic signal intensity greater than or equal to 8. Each column in the heat maps represents the logarithmic signal intensities of each miRNA corresponding to the color gradation. Takao Yasui et al. Sci Adv 2017;3:e1701133 Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).