Performance of the Manchester Acute Coronary Syndromes decision rule in the validation study. Performance of the Manchester Acute Coronary Syndromes decision rule in the validation study. Both MACEs in the very low risk group were coronary stenoses identified on an outpatient basis that did not require intervention. AMI, acute myocardial infarction; MACE, major adverse cardiac events. Richard Body et al. Heart 2014;100:1462-1468 Copyright © BMJ Publishing Group Ltd & British Cardiovascular Society. All rights reserved.