A glomerulus exhibits global wrinkling and retraction of the glomerular basement membrane and diffuse swelling and hyperplasia of overlying visceral epithelial.

Slides:



Advertisements
Similar presentations
Electronic Supplementary Figure 1 A) Light microscopy renal section from a child with HIV demonstrating mesangial expansion with deposits & GBM thickening.
Advertisements

Recurrent Lupus nephritis in the Second Allograft of a Patient with Systemic Lupus erythematosus Nephron 2002;92:947–949 - DOI: / Fig.
A cross-sectional study of HIV-seropositive patients with varying degrees of proteinuria in South Africa  T.M. Han, S. Naicker, P.K. Ramdial, A.G. Assounga 
Volume 65, Issue 5, Pages (May 2004)
Paraneoplastic glomerulopathies: New insights into an old entity
Vivette D D'Agati, MD, Agnes B Fogo, MD, Jan A Bruijn, MD, J
Histologic classification of glomerular diseases: clinicopathologic correlations, limitations exposed by validation studies, and suggestions for modification 
Hypertensive nephrosclerosis in African Americans versus Caucasians
American Journal of Kidney Diseases
J.M. Henderson, S. al-Waheeb, A. Weins, S.V. Dandapani, M.R. Pollak 
Quiz Page MAY 2013 American Journal of Kidney Diseases
The big squeeze: giant cells in granulomatous interstitial nephritis
Quiz Page April 2013 American Journal of Kidney Diseases
Infantile nephropathic cystinosis
Glomerular disease related to anti-VEGF therapy
Sickle Cell Nephropathy
AJKD Atlas of Renal Pathology: Collapsing Glomerulopathy
Apical membrane handling of substances, in this example aminoglycosides, by proximal tubular cells. Apical membrane handling of substances, in this example.
Volume 62, Issue 1, Pages (July 2002)
The spectrum of kidney biopsy findings in patients with morbid obesity
Intra-glomerular metastases
Volume 71, Issue 6, Pages (March 2007)
HIV-associated immune complex glomerulonephritis with “lupus-like” features: A clinicopathologic study of 14 cases1  Mark Haas, Sadhana Kaul, Joseph A.
Dysproteinemia, proteinuria, and glomerulonephritis
M.B. Stokes, A.M. Valeri, G.S. Markowitz, V.D. D'Agati 
AJKD Atlas of Renal Pathology: Pierson Syndrome
Volume 79, Issue 6, Pages (March 2011)
S.H. Nasr, D.C. Preddie, G.S. Markowitz, G.B. Appel, V.D. D'Agati 
American Journal of Kidney Diseases
Volume 84, Issue 1, Pages (July 2013)
Volume 74, Issue 2, Pages (July 2008)
Obesity-related glomerulopathy: An emerging epidemic
Acute Kidney Failure in the Third Trimester of Pregnancy
Pathologic features of interstitial nephritis associated with inflammatory bowel disease. Pathologic features of interstitial nephritis associated with.
HIV-related nephropathy: A South African perspective
Volume 63, Issue 4, Pages (April 2003)
Histopathology of minimal change disease and focal segmental glomerulosclerosis. Histopathology of minimal change disease and focal segmental glomerulosclerosis.
Volume 65, Issue 1, Pages (January 2004)
A cross-sectional study of HIV-seropositive patients with varying degrees of proteinuria in South Africa  T.M. Han, S. Naicker, P.K. Ramdial, A.G. Assounga 
Diabetic glomerulopathy.
Collapsing Glomerulopathy in Lambda Light Chain Amyloidosis: A Report of 2 Cases  Mazdak A. Khalighi, Alexander J. Gallan, Anthony Chang, Shane M. Meehan 
AJKD Atlas of Renal Pathology: Focal Segmental Glomerulosclerosis
Chronic Transplant Glomerulopathy
The NEPTUNE Pathology Scoring System: Examples of descriptors.
Volume 59, Issue 6, Pages (June 2001)
Volume 57, Issue 5, Pages (May 2000)
Acute phosphate nephropathy
Collapsing glomerulopathy.
Membranous and crescentic glomerulonephritis in a patient with anti-nuclear and anti- neutrophil cytoplasmic antibodies  A. Chang, O. Aneziokoro, S.M.
A glomerulus from a patient who developed nephrotic syndrome while receiving a nonsteroidal anti-inflammatory drug for arthritis. A glomerulus from a patient.
Morphologic findings from serial biopsies.
Volume 73, Issue 5, Pages (March 2008)
Glomerulus from a patient with primary membranous nephropathy showing the pathognomonic “spikes” of basement membrane projecting from the outer surface.
Four major patterns of glomerular injury in podocytopathies.
The Ussing Chamber can be used to measure ion transport between the two sides of an epithelial cell membrane by polarized cells. The Ussing Chamber can.
Renal histopathology in anti–glomerular basement membrane (anti-GBM) GN. (A–C) Hematoxylin and eosin–stained sections demonstrating (A) segmental fibrinoid.
Leukocytes in glomeruli of patients with rapidly progressive GN
Basic structure of the glomerulus and the glomerular filtration barrier. Basic structure of the glomerulus and the glomerular filtration barrier. (A) Each.
Christopher P. Larsen, MD, Marjorie L. Beggs, PhD, Patrick D
(A) Photomicrograph depicting typical appearance of a glomerulus in patient with mesangial type lupus nephritis, WHO class II. (Periodic acid-Schiff stain;
Bisphosphonate nephrotoxicity
Cetuximab (C) is an EGF receptor (EGFR) antibody that causes renal magnesium wasting by competing with EGF for its receptor. Cetuximab (C) is an EGF receptor.
A glomerulus exhibits mesangiolysis, endothelial denudation, red blood cell congestion, and glomerular basement membrane duplication in this example of.
Collapsing glomerulopathy (CG) and lesions that may resemble CG histologically in renal biopsies from patients with systemic lupus erythematosus. Collapsing.
Tubulointerstitial changes and arteriolar hyalinosis in diabetic kidney disease. Tubulointerstitial changes and arteriolar hyalinosis in diabetic kidney.
C1q nephropathy: A variant of focal segmental glomerulosclerosis
Incident cases of ESRD secondary to heroin-associated nephropathy, membranoproliferative glomerulonephritis type 1, HIV infection, and focal segmental.
A urine sediment score of 0–4 is used to quantitatively evaluate AKI
Monoclonal Ig deposition disease (MIDD) with diffuse and nodular glomerulosclerosis. Monoclonal Ig deposition disease (MIDD) with diffuse and nodular glomerulosclerosis.
Direct immunofluorescence showing granular mesangial staining for IgA in the expanded mesangium of the biopsy of patient 4, who had underlying diabetic.
Presentation transcript:

A glomerulus exhibits global wrinkling and retraction of the glomerular basement membrane and diffuse swelling and hyperplasia of overlying visceral epithelial cells in this example of collapsing focal segmental glomerulosclerosis. A glomerulus exhibits global wrinkling and retraction of the glomerular basement membrane and diffuse swelling and hyperplasia of overlying visceral epithelial cells in this example of collapsing focal segmental glomerulosclerosis. (Jones methenamine silver stain; original magnification, ×600.) Courtesy of Glen S. Markowitz. Mark A. Perazella CJASN 2012;7:1713-1721 ©2012 by American Society of Nephrology