Orthostatic instability in a population-based study of chronic fatigue syndrome James F. Jones, MD, Ainsley Nicholson, PhD, Rosane Nisenbaum, PhD, Dimitris.

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Orthostatic instability in a population-based study of chronic fatigue syndrome James F. Jones, MD, Ainsley Nicholson, PhD, Rosane Nisenbaum, PhD, Dimitris A. Papanicolaou, Laura Solomon, MPH, Roumiana Boneva, MD, Christine Heim, PhD, William C. Reeves, MD The American Journal of Medicine Volume 118, Issue 12, Pages 1415.e19-1415.e28 (December 2005) DOI: 10.1016/j.amjmed.2005.06.013 Copyright © 2005 Elsevier Inc. Terms and Conditions

Figure 1 Serum osmolality levels and time to orthostatic instability. The American Journal of Medicine 2005 118, 1415.e19-1415.e28DOI: (10.1016/j.amjmed.2005.06.013) Copyright © 2005 Elsevier Inc. Terms and Conditions

Figure 2 Variability of heart rate and blood pressure during the head-up tilt test. The coefficient of variation (CV = standard deviation/mean) was calculated for individuals diagnosed as normal (n = 23), neurally mediated hypotension (n = 6), or postural orthostatic tachycardia (n = 8 recumbent/7 tilted) during the recumbent and tilted portions of the head-up tilt test. Variablility is presented as the mean of individual CVs within each group. Mean CVs that are significantly different from normal (Student’s t test, alpha = 0.05) are present in the tilted neurally mediated hypotension component of the figure. NMH = neurally mediated hypotension; POT = postural orthostatic tachycardia. The American Journal of Medicine 2005 118, 1415.e19-1415.e28DOI: (10.1016/j.amjmed.2005.06.013) Copyright © 2005 Elsevier Inc. Terms and Conditions