Treatment of minor wounds from dermatologic procedures: A comparison of three topical wound care ointments using a laser wound model Nathan S. Trookman,

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Treatment of minor wounds from dermatologic procedures: A comparison of three topical wound care ointments using a laser wound model Nathan S. Trookman, MD, FAAD, Ronald L. Rizer, PhD, Teresa Weber, PhD Journal of the American Academy of Dermatology Volume 64, Issue 3, Pages S8-S15 (March 2011) DOI: 10.1016/j.jaad.2010.11.011 Copyright © 2011 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Mean clinical grading scores of wound sites treated with AHO, Poly/Bac, Poly/Bac/Neo, and untreated site. A, Erythema. B, Edema. C, Epithelial confluence. D, Scabbing. Erythema and edema grading scale: 0 = none, 1 = mild, 2 = moderate, 3 = marked, 4 = severe. Epithelial confluence grading scale: 0 = none, 1 = slight, 2 = moderate, 3 = extensive, 4 = complete or almost complete. Scabbing grading scale: 0 = none, 1 = slight, 2 = moderate, 3 = extensive, 4 = complete or almost complete. P values significantly different from: all other treatmentsa; Poly/Bac and Poly/Bac/Neob; untreated site scorec; and AHO.d Journal of the American Academy of Dermatology 2011 64, S8-S15DOI: (10.1016/j.jaad.2010.11.011) Copyright © 2011 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Transepidermal water loss (TEWL). Instrumental analysis of water loss caused by damage of stratum corneum in g/m2/h. aP value significantly different from all other treatments (P = .0006). Journal of the American Academy of Dermatology 2011 64, S8-S15DOI: (10.1016/j.jaad.2010.11.011) Copyright © 2011 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Investigator grading of general wound appearance (mean scores). Wound appearance grading scale: 0 = poor, 1 = fair, 2 = good, 3 = very good, 4 = excellent. P values significantly different from: all other treatmentsa; and untreated site score.b Journal of the American Academy of Dermatology 2011 64, S8-S15DOI: (10.1016/j.jaad.2010.11.011) Copyright © 2011 American Academy of Dermatology, Inc. Terms and Conditions

Fig 4 Progression of wound healing in individual subjects from day 1 to 18. Magnified results shown for day 7 to 18. Subjects 1 (A) and 2 (B). Journal of the American Academy of Dermatology 2011 64, S8-S15DOI: (10.1016/j.jaad.2010.11.011) Copyright © 2011 American Academy of Dermatology, Inc. Terms and Conditions