Volume 157, Issue 3, Pages e2 (September 2019)

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Volume 157, Issue 3, Pages 682-691.e2 (September 2019) Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin  Paul Moayyedi, John W. Eikelboom, Jackie Bosch, Stuart J. Connolly, Leanne Dyal, Olga Shestakovska, Darryl Leong, Sonia S. Anand, Stefan Störk, Kelley R.H. Branch, Deepak L. Bhatt, Peter B. Verhamme, Martin O’Donnell, Aldo P. Maggioni, Eva M. Lonn, Leopoldo S. Piegas, Georg Ertl, Matyas Keltai, Nancy Cook Bruns, Eva Muehlhofer, Gilles R. Dagenais, Jae-Hyung Kim, Masatsugu Hori, P. Gabriel Steg, Robert G. Hart, Rafael Diaz, Marco Alings, Petr Widimsky, Alvaro Avezum, Jeffrey Probstfield, Jun Zhu, Yan Liang, Patricio Lopez- Jaramillo, Ajay K. Kakkar, Alexander N. Parkhomenko, Lars Ryden, Nana Pogosova, Antonio L. Dans, Fernando Lanas, Patrick J. Commerford, Christian Torp-Pedersen, Tomek J. Guzik, Dragos Vinereanu, Andrew M. Tonkin, Basil S. Lewis, Camilo Felix, Khalid Yusoff, Kaj P. Metsarinne, Keith A.A. Fox, Salim Yusuf  Gastroenterology  Volume 157, Issue 3, Pages 682-691.e2 (September 2019) DOI: 10.1053/j.gastro.2019.05.056 Copyright © 2019 AGA Institute Terms and Conditions

Figure 1 Consort diagram. Gastroenterology 2019 157, 682-691.e2DOI: (10.1053/j.gastro.2019.05.056) Copyright © 2019 AGA Institute Terms and Conditions

Figure 2 Cumulative incidence of combined cardiovascular death, myocardial infarction, and stroke in the pantoprazole vs placebo arm. Gastroenterology 2019 157, 682-691.e2DOI: (10.1053/j.gastro.2019.05.056) Copyright © 2019 AGA Institute Terms and Conditions

Figure 3 Cumulative incidence of individual cardiovascular events in the pantoprazole vs placebo arm. Gastroenterology 2019 157, 682-691.e2DOI: (10.1053/j.gastro.2019.05.056) Copyright © 2019 AGA Institute Terms and Conditions