DegrAAAded into Silence

Slides:

Advertisements

Similar presentations

UpSET Recruits HDAC Complexes and Restricts Chromatin Accessibility and Acetylation at Promoter Regions Hector Rincon-Arano, Jessica Halow, Jeffrey J.

Advertisements

The Bacterial DnaC Helicase Loader Is a DnaB Ring Breaker Ernesto Arias-Palomo, Valerie L. O’Shea, Iris V. Hood, James M. Berger Cell Volume 153, Issue.

Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E Yumi Kim, Andrew J. Holland, Weijie Lan, Don W. Cleveland.

Profiling by Image Registration Reveals Common Origin of Annelid Mushroom Bodies and Vertebrate Pallium Raju Tomer, Alexandru S. Denes, Kristin Tessmar-Raible,

SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages (January.

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells Jenny M. Karo, David G. Schatz, Joseph C. Sun Cell Volume.

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity Jenni Durieux, Suzanne Wolff, Andrew Dillin Cell Volume 144, Issue 1, Pages.

Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding J. Winter, M. Ilbert, P.C.F. Graf, D. Özcelik, U. Jakob Cell Volume 135, Issue.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Treatment of Obesity with Celastrol

Origins of Metastatic Traits Sakari Vanharanta, Joan Massagué Cancer Cell Volume 24, Issue 4, Pages (October 2013) DOI: /j.ccr

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Transcriptional Control of Gene Expression by MicroRNAs Basel Khraiwesh, M. Asif Arif, Gotelinde I. Seumel, Stephan Ossowski, Detlef Weigel, Ralf Reski,

Common Sense about Taste: From Mammals to Insects David A. Yarmolinsky, Charles S. Zuker, Nicholas J.P. Ryba Cell Volume 139, Issue 2, Pages (October.

Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm Jianbin Wang, H. Christina Fan, Barry Behr, Stephen.

UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke Jae Young Lee, Wei Yang Cell Volume 127, Issue 7, Pages (December.

Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome Corinne Ferrier Maurice, Henry Joseph Haiser, Peter James Turnbaugh.

Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.

RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity Jean-Baptiste Vannier, Visnja Pavicic-Kaltenbrunner, Mark I.R.

Molecular Basis for Coordinating Transcription Termination with Noncoding RNA Degradation Agnieszka Tudek, Odil Porrua, Tomasz Kabzinski, Michael Lidschreiber,

Nucleocapsid Phosphorylation and RNA Helicase DDX1 Recruitment Enables Coronavirus Transition from Discontinuous to Continuous Transcription Chia-Hsin.

The Monarch Butterfly Genome Yields Insights into Long-Distance Migration Shuai Zhan, Christine Merlin, Jeffrey L. Boore, Steven M. Reppert Cell Volume.

Dynein Anchors Its mRNA Cargo after Apical Transport in the Drosophila Blastoderm Embryo Renald Delanoue, Ilan Davis Cell Volume 122, Issue 1, Pages

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell

Transmembrane Receptor DCC Associates with Protein Synthesis Machinery and Regulates Translation Joseph Tcherkezian, Perry A. Brittis, Franziska Thomas,

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.

SRC-3 Coactivator Functional Lifetime Is Regulated by a Phospho-Dependent Ubiquitin Time Clock Ray-Chang Wu, Qin Feng, David M. Lonard, Bert W. O'Malley.

WHAMM Is an Arp2/3 Complex Activator That Binds Microtubules and Functions in ER to Golgi Transport Kenneth G. Campellone, Neil J. Webb, Elizabeth A. Znameroski,

Mutually Exclusive Binding of Telomerase RNA and DNA by Ku Alters Telomerase Recruitment Model Jennifer S. Pfingsten, Karen J. Goodrich, Cornelius Taabazuing,

Sensory Detection of Food Rapidly Modulates Arcuate Feeding Circuits Yiming Chen, Yen-Chu Lin, Tzu-Wei Kuo, Zachary A. Knight Cell Volume 160, Issue 5,

SSB Functions as a Sliding Platform that Migrates on DNA via Reptation Ruobo Zhou, Alexander G. Kozlov, Rahul Roy, Jichuan Zhang, Sergey Korolev, Timothy.

IL-33, Imprimatur of Adipocyte Thermogenesis

Unweaving the Autism Spectrum

Heavy Metal Enlightens Tumor Immunity

Linking Protein and RNA Function within the Same Gene

The Proteasome: Not Just Degrading Anymore

A PASport to Cellular Proliferation

Volume 154, Issue 1, Pages (July 2013)

In This Issue Cell Volume 158, Issue 5, (August 2014)

Volume 152, Issue 1, (January 2013)

Volume 133, Issue 1, Pages (April 2008)

The Role of the RNAi Machinery in Heterochromatin Formation

Volume 130, Issue 6, (September 2007)

Volume 64, Issue 3, Pages (November 2016)

A Lifelong Passion for All Things Ribonucleic

Proteins Kinases: Chromatin-Associated Enzymes?

When Biology Doesn’t Add Up

Easy Stress Relief by EZH2

Volume 143, Issue 6, (December 2010)

RNA Quality Control in Eukaryotes

Making the Most from Changes in Life

The Cell Biology of Genomes: Bringing the Double Helix to Life

Transcriptional Pausing Caught in the Act

Pok Kwan Yang, Mitzi I. Kuroda Cell

Learning from the Uncontrollable

Silencing the Transcriptome's Dark Matter: Mechanisms for Suppressing Translation of Intergenic Transcripts Kellie S. Bickel, David R. Morris Molecular.

Transcriptional Scaffolds for Heterochromatin Assembly

Volume 163, Issue 4, (November 2015)

Volume 61, Issue 2, Pages (January 2016)

Volume 163, Issue 2, (October 2015)

Epigenome Sequencing Comes of Age

Volume 134, Issue 6, (September 2008)

In This Issue Cell Volume 145, Issue 3, (April 2011)

Volume 148, Issue 1, (January 2012)

Presentation transcript:

DegrAAAded into Silence Elizabeth H. Bayne, Sharon A. White, Robin C. Allshire Cell Volume 129, Issue 4, Pages 651-653 (May 2007) DOI: 10.1016/j.cell.2007.05.004 Copyright © 2007 Elsevier Inc. Terms and Conditions

Figure 1 Silencing Heterochromatin in Fission Yeast Noncoding RNA transcripts originating from heterochromatin repeats, or transgene insertions within heterochromatin, may be polyadenylated by Cid14. The transcript may be polyadenylated directly upon termination of transcription, or alternatively transcripts may be first sliced by Ago1 and then polyadenylated by Cid14. This may “mark” the transcript for degradation and/or processing via the RNAi machinery, RDRC/Dcr1, or the exosome. Cell 2007 129, 651-653DOI: (10.1016/j.cell.2007.05.004) Copyright © 2007 Elsevier Inc. Terms and Conditions