The kinetics of change in cytokine production by CD4+ T cells during conventional allergen immunotherapy Suwat Benjaponpitak, MDa, Amy Oro, MDa, Peter.

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Presentation transcript:

The kinetics of change in cytokine production by CD4+ T cells during conventional allergen immunotherapy Suwat Benjaponpitak, MDa*, Amy Oro, MDa*, Peter Maguire, MDa, Vince Marinkovich, b, Rosemarie H. DeKruyff, PhDa, Dale T. Umetsu, MD, PhDa Journal of Allergy and Clinical Immunology Volume 103, Issue 3, Pages 468-475 (March 1999) DOI: 10.1016/S0091-6749(99)70473-2 Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 1 Serum allergen–specific IgE during conventional immunotherapy. Allergen-specific IgE to treatment allergen (rye grass allergen) decreased during the course of therapy in a responder patient (subject number 1). Results represent international units per milliliter by using the Pharmacia CAP IgE FEIA assay. Allergen-specific IgE against a nontreatment allergen D farinae (Der. f.) in the same patient rose during immunotherapy. The results represent luminescence units by using the MAST CLA allergy system. Journal of Allergy and Clinical Immunology 1999 103, 468-475DOI: (10.1016/S0091-6749(99)70473-2) Copyright © 1999 Mosby, Inc. Terms and Conditions

Fig. 2 Serum allergen–specific IgE to a treatment allergen, D farinae (Der. f. ), but not to a nontreatment allergen, L perenne (Lol. p. ), increased during conventional immunotherapy in the nonresponder subject (subject number 6). Results represent luminescence units by using the MAST CLA allergy system. Journal of Allergy and Clinical Immunology 1999 103, 468-475DOI: (10.1016/S0091-6749(99)70473-2) Copyright © 1999 Mosby, Inc. Terms and Conditions