Axial 1advanced technology laboratory animal scanner PET images of [11C]DCMC in (A) MCF-7 and (B) PC-3 tumor-bearing mice. Axial 1advanced technology laboratory.

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Axial 1advanced technology laboratory animal scanner PET images of [11C]DCMC in (A) MCF-7 and (B) PC-3 tumor-bearing mice. Axial 1advanced technology laboratory animal scanner PET images of [11C]DCMC in (A) MCF-7 and (B) PC-3 tumor-bearing mice. Pre-blockade images (left mouse) and those with coinjection of 50 mg/kg PMPA blocker (right mouse). PMPA decreased uptake within renal cortex (site of proximal tubules, replete with PSMA), but neither of these PSMA-negative tumors could be imaged clearly with this agent. Catherine A. Foss et al. Clin Cancer Res 2005;11:4022-4028 ©2005 by American Association for Cancer Research