PTRF Triggers a Cave In Cell

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PTRF Triggers a Cave In Cell Rahul Chadda, Satyajit Mayor Cell Volume 132, Issue 1, Pages 23-24 (January 2008) DOI: 10.1016/j.cell.2007.12.021 Copyright © 2008 Elsevier Inc. Terms and Conditions

Figure 1 PTRF in the Life Cycle of Caveolin Caveolin proteins (orange) are delivered to the cell surface, where they can associate with PTRF (green) and generate flask-shaped caveolae. Downregulation of PTRF renders caveolin mobile in the plasma membrane, at which point it can be endocytosed and rapidly degraded. Inset image of caveolae is reproduced from Rothberg et al. (1992). Cell 2008 132, 23-24DOI: (10.1016/j.cell.2007.12.021) Copyright © 2008 Elsevier Inc. Terms and Conditions