Effect of microRNA (miR)-17-loaded lipid–polymer hybrid nanoparticles (LPNs) on interleukin (IL)-8 expression. Effect of microRNA (miR)-17-loaded lipid–polymer.

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Effect of microRNA (miR)-17-loaded lipid–polymer hybrid nanoparticles (LPNs) on interleukin (IL)-8 expression. Effect of microRNA (miR)-17-loaded lipid–polymer hybrid nanoparticles (LPNs) on interleukin (IL)-8 expression. LPS: lipopolysaccharide; BEC: bronchial epithelial cell; LD: low density (NuLi-1 BECs cultured to subconfluent density); HD: high density (NuLi-1 BECs cultured at confluent density). a, c) Baseline and b, d) LPS-stimulated IL-8 expression in a, b) LD and c, d) HD NuLi-1 BEC cultures exposed to 25, 50 and 100 µg·cm−2 miR-17-loaded LPNs or NC#1-loaded LPNs. Individual data points are shown; bars represent mean values. *: p≤0.05; **: p≤0.01, one-tailed ratio t-test. n=6 for LD; n=4 for HD. Sebastian Vencken et al. ERJ Open Res 2019;5:00161-2018 ©2019 by European Respiratory Society