MHE diagnosis – Stroop test Brain MRI findings in liver cirrhosis patients with subclinical hepatic encephalopathy Lupescu IC1, Iacob S2,4, Lupescu IG3,4, Gheorghe L2,4 1Neurology Department, Fundeni Clinical Institute, Bucharest, Romania 2Gastroenterology Department, Fundeni Clinical Institute, Bucharest, Romania 3Radiology and Medical Imaging Department, Fundeni Clinical Institute, Bucharest, Romania 4Carol Davila University of Medicine and Pharmacy, Bucharest, Romania BACKGROUND: Liver cirrhosis AIM: To correlate MATERIAL AND METHODS: RESULTS: CONCLUSIONS: Hepatic encephalopathy Acquired hepato-cerebral degeneration Hepatic myelopathy Bilateral symmetric T1-hyperintensities of the globus pallidus and substantia nigra Brain MRI findings Presence of minimal hepatic encephalopathy (MHE) Inclusion criteria Liver cirrhosis No overt HE 18-65 years-old MHE diagnosis – Stroop test ≥ 145 seconds for patients <45 years-old >190 seconds for patients ≥45 years-old MRI – 1.5 Tesla T1, T2, FLAIR, GRE, DWI, SWI, Spectroscopy 30 patients Mean age = 50.2 ± 9.9 years-old < 45 years-old: n=7 ≥ 45 years-old: n=23 < 45 yo ≥ 45 yo p MELD 16 ± 5 14 ± 5 0.3 Child 8 ± 2 0.6 No correlation was found between presence of brain MRI abnormalities and MHE diagnosis Fischer exact test: p=0.12