High tissue affinity angiotensin-converting enzyme inhibitors improve endothelial function and reduce infarct size Harold L Lazar, MD, Yusheng Bao, MD,

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Presentation transcript:

High tissue affinity angiotensin-converting enzyme inhibitors improve endothelial function and reduce infarct size Harold L Lazar, MD, Yusheng Bao, MD, Samuel Rivers, BS, Theodore Colton, Sheilah A Bernard, MD The Annals of Thoracic Surgery Volume 72, Issue 2, Pages 548-553 (August 2001) DOI: 10.1016/S0003-4975(01)02779-5

Fig 1 Vascular relaxation. (A) Endothelium-independent nitroglycerin. (B) Endothelium-dependent A23187. (C) Endothelium-dependent bradykinin. All values represent the mean ± standard error. ∗p < 0.001 from no ACE, enalaprilat 0.05 mg/kg, enalaprilat 0.3 mg/kg; †p < 0.001 from quinaprilat plus HOE 140. (ACE = angiotensin-converting enzyme.) The Annals of Thoracic Surgery 2001 72, 548-553DOI: (10.1016/S0003-4975(01)02779-5)