Infant 2, an 11-month-old Cree girl with hypotonia and developmental regression. Infant 2, an 11-month-old Cree girl with hypotonia and developmental regression.

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High-signal-intensity lesions on T2-weighted MR images

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Presentation transcript:

Infant 2, an 11-month-old Cree girl with hypotonia and developmental regression. Infant 2, an 11-month-old Cree girl with hypotonia and developmental regression. A−C, Axial CT images demonstrate diffuse bilateral symmetric hypoattenuation of the cerebral and cerebellar white matter. D−F, Axial T2 images demonstrate bilateral symmetric T2 hyperintensity of the cerebral white matter, substantia nigra (small white arrow), and globus pallidus (large white arrow), with involvement of the thalami (black arrow) and sparing of the caudate nuclei, red nucleus, and putamen. S. Harder et al. AJNR Am J Neuroradiol 2010;31:1418-1423 ©2010 by American Society of Neuroradiology