Jing Zhao, MD, Hang Li, MD, Mengzhao Wang, MD

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Presentation transcript:

Acute Renal Failure in a Patient Receiving Anti-VEGF Therapy for Advanced Non-small Cell Lung Cancer Jing Zhao, MD, Hang Li, MD, Mengzhao Wang, MD Journal of Thoracic Oncology Volume 4, Issue 9, Pages 1185-1187 (September 2009) DOI: 10.1097/JTO.0b013e3181b2362f Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 A, The mesangial matrix increase was more severe in peripheral areas of the tuft, giving the glomerular tuft a “lobular” appearance. B, Basement membrane thickening was due to mesangial cell interposition along the subendothelial area with consequent neoformation of basement membrane that gave the morphologic aspect of “double contour.” C, It showed bright diffuse gr1nular glomerular capillary wall and mesangial staining for C3. D, The image showed the concomitant presence of subendothelial and subepithelial deposits. A mesangial cell migrated to the subendothelial side of the lamina densa. Journal of Thoracic Oncology 2009 4, 1185-1187DOI: (10.1097/JTO.0b013e3181b2362f) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions