Challenges http://www.girihlet.com.

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Presentation transcript:

Challenges http://www.girihlet.com

Deep Sequencing Signatures Problems Genomic data deluge from TCR repertoire sequencing Problems: Data management, Visualization, Analyses GOAL: Build a diagnostic tool Millions of cells BLOOD B-Cell T-Cell INFECTION T-SEQ Deep Sequencing Signatures IMMUNE SYSTEM

Tools Sequencers, Robots, Servers (cloud and local) Covaris Local Servers QIAcube robot (DNA / RNA extractions) Illumina Sequencer Covaris Bioanalyzer Hudson Robotics OpenTrons

Missing: Data Scientists, Bioinformaticists Manage the data deluge Team 2 Computational scientists 2 Research Scientists 2 Technicians 1 Lab Manager Founders: Ravi and Anitha Missing: Data Scientists, Bioinformaticists Manage the data deluge Generate understanding

Projects Handle sequencing data from a variety of samples Develop algorithms for analyzing TCR data Develop methods to identify patterns in TCR and mtDNA data. Develop databases and methods of visualizing data