The Nurse View: Practice Pearls in the Use of Immune Checkpoint Inhibitors in Advanced NSCLC.

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Presentation transcript:

The Nurse View: Practice Pearls in the Use of Immune Checkpoint Inhibitors in Advanced NSCLC

Checkpoint Inhibitors Approved in NSCLC

Immunotherapy vs Chemotherapy

Overview of Immune Regulation

Basics of Immunotherapy

CheckMate Trial Design

KEYNOTE Trial Design

Outcomes With Pembrolizumab

KEYNOTE-024 Trial Design

OAK Trial Design

Most Common TRAEs With Immunotherapy

Management of AEs

Grading of AEs

Management of irAEs Based on Grade

Management of Diarrhea/Colitis

Management of Pneumonitis

Management of Steroid-Refractory irAEs

Restarting Immunotherapy

Management of Hypothyroidism

Importance of Patient Education

The Future of Immunotherapy

Key Takeaways

Abbreviations

Abbreviations (cont)