Quantifying biochemical changes in the cartilage matrix in osteoarthritic knee after hyaluronic acid injection using quantitative MR techniques A.R.

Slides:

Advertisements

Similar presentations

The effects of polyacrylamide hydrogel in normal and osteoarthritic animal joints L.H. Christensen, L. Camitz, K.E. Illigen, M. Hansen, R. Sarvaa, P.G.

Advertisements

Changes in the T2 relaxation value of the tibiofemoral articular cartilage about 6 months after anterior cruciate ligament reconstruction using the double-bundle.

MRI-Based T2 Knee Cartilage Texture Analysis Can Differentiate Subjects With and Without History of Knee Injury Despite Similar Morphological Scores:

T1ρ and T2 relaxation times predict progression of knee osteoarthritis

3D Knee Bone Shape Predisposes to ACL Rupture: Data from the Osteoarthritis Initiative and the Kanon Study M.A. Bowes, S. Lohmander, P.G. Conaghan, R.

A. Bhave, M. Mont, M. Chugthai, R. Starr Osteoarthritis and Cartilage

R. Takeuchi, H. Ishikawa, T. Kuniya, A. Nakazawa

S. Gavard Osteoarthritis and Cartilage

Isotropic three-dimensional T2 mapping of knee cartilage with T2-prepared segmented gradient ECHO at 3T R. Colotti, P. Omoumi, R.B. van Heeswijk Osteoarthritis.

Knee joint space width progression: results of a 3

Prospective economic evaluation of the costs for medications and nutraceuticals in knee osteoarthritis M. Chung, N. Zhao, J.B. Wong, C. Wang Osteoarthritis.

A novel fast knee cartilage segmentation technique for T2 measurements at MR imaging – data from the Osteoarthritis Initiative C. Stehling, T. Baum,

Relationship between trabecular bone structure and articular cartilage morphology and relaxation times in early OA of the knee joint using parallel MRI.

Bone shape does not cause OA – But OA does change bone shape; a study on data from 4654 knees from the Osteoarthritis Initiative M.A. Bowes, C.B. Wolstenholme,

Does a yoga-strengthening program for women with knee osteoarthritis have an effect on gait patterns? An investigation with principal components analysis

Advances in visualization of knee cartilage and meniscal morphology with standing computed tomography N.A. Segal, A. Guermazi Osteoarthritis and Cartilage

Presence of cartilage lesions at the time of injury influences the longitudinal progression of T1ρ and T2 6 months after anterior cruciate ligament injury

Biochemical markers of synovial inflammation – Surrogate markers of synovitis on magnetic resonance imaging? – Data from the osteoarthritis initiative

K. Amano, A.K. Li, V. Pedoia, S. Rodeo, X. Li, C. Ma, S. Majumdar

Prevention and treatment of intervertebral disc degeneration with bone marrow derived stem (stromal) cells – an in vivo study in sheep C.C. Shu, A. Dart,

Quantitatively-measured bone marrow lesions in the patellofemoral joint: distribution and association with pain C. Ratzlaff, R. Russell, J. Duryea Osteoarthritis.

Role of endothelin-1 in endochondral ossification and osteoarthritis

Association between tibial subchondral bone structure from plain radiographs and cartilage composition from quantitative MRI in postmenopausal women with.

Automatic cartilage segmentation and measurement for diagnosis of OA using 3D box and Gaussian filters X. Cui, S. Li, M. Yu, H. Kim, K.-S. Kwack, B.-H.

Mineralization of meniscal enthesis in osteoarthritic knees

Effect of self assembled peptide-mesenchymal stem cell complex on delaying the progression of osteoarthritis S. Kim, S. Lee, Y. Jung, J. Kim, S. Kim

Quantitative T1ρ, T2 and T2* mapping of articular cartilage changes in a rat model of osteoarthritis using in vivo high-resolution magnetic resonance.

G. Venne, S. Pang, Y. Tse, R. Ellis Osteoarthritis and Cartilage

Osteoarthritis and Cartilage

M.C. Gallo, V. Pedoia, T.M. Link, R.B. Souza, S. Majumdar

Prospective changes in cartilage thickness correlate with knee kinematics at peak loading during walking following anterior cruciate ligament reconstruction

Replicability of recommended exercise interventions for knee osteoarthritis: a descriptive systematic review of current clinical guidelines and recommendations

Maintaining sufficient serum vitamin d levels over two years is associated with improved knee structural and symptomatic outcomes in people with knee.

P. Yuan, X. Zhang, W. Yang, W. Kang, B. Yang, J. li, B. Chen, X. Li, B

Association of ultrasound-defined structural changes with regional and diffuse knee pain patterns – Oulu Knee Osteoarthritis study J. Podlipská, P. Kaukinen,

Assessing the characteristics of human mesenchymal stromal cells derived from bone marrow and umbilical cord following expansion in the quantum® hollow-fibre.

Two different knee braces alter patella position: a moving image analysis using weight bearing magnetic resonance imaging M.J. Callaghan, N.D. Reeves,

The influence of early osteoarthritic collagen network de-structuring in articular cartilage on the tissue stiffness and swelling properties M. Nickien,

N. Bodick, J. Lufkin, C. Willwerth, A. Kumar, J. Bolognese, C

R2−R1ρ as a Potential Biomarker for Tracking Cartilage Matrix Changes in Osteoarthritic Knees after Hyaluronic Acid Injection M. Tanaka, A. Azus, V.

A new lipid formulation of low dose (1200mg) ibuprofen is non-inferior to high dose (2400mg) standard ibuprofen capsules in managing episodic knee pain.

Osteoarthritis and Cartilage

The effects of polyacrylamide hydrogel in normal and osteoarthritic animal joints L.H. Christensen, L. Camitz, K.E. Illigen, M. Hansen, R. Sarvaa, P.G.

B. C. Roberts, D. Thewlis, L. B. Solomon, G. Mercer, K. J. Reynolds, E

A cartilage-targeted insulin-like growth factor-1 is retained in cartilage and promotes extracellular matrix maintenance in rat medial meniscus tear model

M. F. Pustjens, S. C. Mastbergen, W. H. Noort-Van der Laan, R. J

Patellofemoral Bone Morphology is Related to Gender But Not Pain: 3D Quantitative Data Analysis From The OAI M.A. Bowes, B.T. Drew, A.C. Redmond, B.

Patients with abnormal limb kinetics at six months after anterior cruciate ligament reconstruction have a potential risk for medical meniscus abnormality.

Three dimensional distribution of hip cartilage t2 mapping assessed by radial mr imaging: comparison between healthy volunteers and patients with hip.

Emerging role of endothelin receptor type B in regulating chondrogenic and hypertrophic changes of human mesenchymal stem cells M. Au, M. Zhu, W.-J.

Medial meniscus posterior horn zones show differing responses to static loading in subjects with knee osteoarthritis compared to controls N.E. Calixto,

N. Khalaj, N.A. Osman, W. Wan Abas, A. Mokhtar

Z. Huang, T. Stabler, F. Pei, V. Kraus Osteoarthritis and Cartilage

Elevated cartilage T2 and increased severity of cartilage defects at baseline are associated with the development of knee pain over 7 years G.B. Joseph,

Low-dose SoluMatrix meloxicam results in clinically meaningful improvements in pain in a phase 3 study of patients with osteoarthritis R. Altman, M.

Evidence for bone mineral density and bone resorption in middle and elderly women with knee osteoarthritis in Shanghai: a cross sectional study Q. Xiaofeng

The association between hip bone marrow lesions and bone mineral density: a cross- sectional and longitudinal population-based study H. Ahedi, D. Aitken,

Walking with increased foot progression angle can reduce joint compression in individuals with knee OA K. Manal, T.S. Buchanan Osteoarthritis and Cartilage

Multivariate pattern analysis of physical activity and cartilage health: data from the osteoarthritis initiative E. Halilaj, T.J. Hastie, G.E. Gold,

Imaging biomarker with T1 and T2 mappings in osteoarthritis – In vivo human articular cartilage study C. Yan, C. Wong, T. Li, N. Gong, Q. Chan, K. Chiu

Longitudinal evaluation of T1ρ and T2 spatial distribution in osteoarthritic and healthy medial knee cartilage J. Schooler, D. Kumar, L. Nardo, C. McCulloch,

How does lower leg alignment differ between soccer players, other athletes and non- athletic controls? W. colyn, R. Agricola, N. Arnout, J. Verhaar, J.

Knee kinematic and kinetic modifications under body weight unloading during overground walking at a constant speed A.G. Fischer, E.M. Debbi, A. Wolf

The Effect of Oral PC-III on Osteoarthritis and Bone Marrow Lesions

Knee kinematic differences in anterior cruciate ligament deficient subjects prior to reconstruction is associated with knee T1ρ cartilage relaxation time.

In situ evaluation of chondrofix® osteochondral allograft 25 months following implantation: A case report K.L. Reynolds, S.K. Bishai Osteoarthritis.

Altered biomechanics and cartilage health changes in bilateral knees following unilateral ACL reconstruction: a 2-year follow-up J.K. Ochoa, K. Amano,

Osteoarthritis and Cartilage

General Information Osteoarthritis and Cartilage

Long-term effects of vitamin d supplementation and maintaining vitamin d sufficiency on knee osteoarthritis over 5 years B. Antony, S. Zheng, J. Burgess,

Presentation transcript:

Quantifying biochemical changes in the cartilage matrix in osteoarthritic knee after hyaluronic acid injection using quantitative MR techniques A.R. Azus, K. Amano, F. Su, M. Tanaka, J. Gong, X. Li Osteoarthritis and Cartilage Volume 24, Pages S506-S507 (April 2016) DOI: 10.1016/j.joca.2016.01.925 Copyright © 2016 Terms and Conditions

Figure 1a. T1ρ values at Baseline, 1 week, 3 month follow up Figure 1a. T1ρ values at Baseline, 1 week, 3 month follow up. MFC = medial femoral ondyle; MT = medial tibia; PAT = patella; TRO = trochlea. *p < 0.005. Osteoarthritis and Cartilage 2016 24, S506-S507DOI: (10.1016/j.joca.2016.01.925) Copyright © 2016 Terms and Conditions

Figure 1b. T2 values at baseline, 1 week, 3 month follow up. p < 0 Osteoarthritis and Cartilage 2016 24, S506-S507DOI: (10.1016/j.joca.2016.01.925) Copyright © 2016 Terms and Conditions

Figure 2: KOOS scores at baseline, 1 week, and 3 month follow up. Osteoarthritis and Cartilage 2016 24, S506-S507DOI: (10.1016/j.joca.2016.01.925) Copyright © 2016 Terms and Conditions

Figure 3. Effusion and bone marrow edema-like lesion scores at baseline. 1 week, and 3 month follow up. Osteoarthritis and Cartilage 2016 24, S506-S507DOI: (10.1016/j.joca.2016.01.925) Copyright © 2016 Terms and Conditions