The invasive isolate has higher levels of intracellular glutathione following exposure to oxidative stress. The invasive isolate has higher levels of intracellular glutathione following exposure to oxidative stress. (A) The decreased expression of sulfate assimilation genes in the carriage-associated isolates from the NZ97/192 household leads to lower levels of intracellular glutathione following exposure to 5 mM hydrogen peroxide. *, P < 0.05. (B) No significant difference was seen in survival rates in the presence of 2 or 5 mM hydrogen peroxide for 20 min. Error bars represent standard deviations. Xiaoyun Ren et al. mSystems 2017; doi:10.1128/mSystems.00127-17