Analysis of absolute CD4+ cytokine+ cell numbers pre- and post-ART.

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Presentation transcript:

Analysis of absolute CD4+ cytokine+ cell numbers pre- and post-ART. Analysis of absolute CD4+ cytokine+ cell numbers pre- and post-ART. PBMCs from patients prior to and at 12 mo of ART were simulated with EC, PPD, HIV, or anti-CD3/CD28 overnight and analyzed for absolute levels of CD4+IFN-γ+, IL-2+, TNF-α+, or total cytokine-positive cells. A–D, Absolute number of cytokine positive cells after anti-CD3/CD28 (A), HIV-1 (B), EC (C), or PPD (D) stimulation. Bar indicates median of 16 patients (pre-ART, filled circles; post-ART, open circles). Data were analyzed using a Wilcoxon matched t test and p values are indicated. Jayne S. Sutherland et al. J Immunol 2010;184:6537-6544 Copyright © 2010 by The American Association of Immunologists, Inc.