Fig. 5. High burdens of AA signature mutations and predicted immunogenicity in Taiwan HCCs. High burdens of AA signature mutations and predicted immunogenicity.

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Fig. 5. High burdens of AA signature mutations and predicted immunogenicity in Taiwan HCCs. High burdens of AA signature mutations and predicted immunogenicity in Taiwan HCCs. (A) AA signature mutations constitute the majority of mutations in most Taiwan HCCs affected by the AA mutational signature. (B) Many more in silico predicted candidate neoantigens in AA HCCs than non-AA HCCs; P value by Wilcoxon rank sum test. Alvin W. T. Ng et al., Sci Transl Med 2017;9:eaan6446 Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works