Pulmonary vascular resistance (PVR; dyn/s/cm) at baseline and after exposure to inhaled nitric oxide (INO; 20 ppm) for 10 min, inhaled epoprostenol (EPO;

Slides:



Advertisements
Similar presentations
Effect of nasal positive expiratory pressure (PEP) on 6-min walk test (6MWT) distance and pre- to post-exercise increase in lung volumes in each individual.
Advertisements

Forest plot of the diagnostic yield of combined transbronchial needle aspiration (TBNA) and transbronchial lung biopsy (TBLB) in patients with sarcoidosis.
Timothy W. Higenbottam, MD, FCCP, Elizabeth A. Laude, PhD  CHEST 
Is Upfront Triple Combination Therapy in PAH "A Thing"?
The changes in peak flow and inspiratory time between a minimum rise time (first 2 breaths) and a maximum rise time (last 2 breaths), with the Servo-i.
Physiological changes in pulmonary arterial hypertension (PAH) patients which occur in response to pregnancy. Physiological changes in pulmonary arterial.
Trigger pressure-time product (PTP) with zero pressure support, with no leak, medium leak, and large leak. Trigger pressure-time product (PTP) with zero.
Spearman rank correlation between absolute humidity and the patient's core temperature with the Humid-Heat device. Spearman rank correlation between absolute.
Spiral computed tomography pulmonary angiogram 8 months after radiofrequency ablation. Spiral computed tomography pulmonary angiogram 8 months after radiofrequency.
Schematic illustration of upper airway anatomical dead space volume (VD) during unidirectional breathing. Schematic illustration of upper airway anatomical.
Matrix used to calculate the kappa statistic.
The effect of sequential addition of sildenafil to first-line epoprostenol on exercise capacity measured using 6-min walk distance (6MWD) in the PACES.
In acute lung injury, inhaled nitric oxide improves ventilation-perfusion matching, pulmonary vascular mechanics, and transpulmonary vascular efficiency 
Picture of bubble PEP devices.
Nitric Oxide Dose Response During Moderate and Severe Hypoxia in Swine
Simulated screenshot of flow starvation in volume control continuous mandatory ventilation. Simulated screenshot of flow starvation in volume control continuous.
A: Computed tomogram shows bilateral dependent consolidation in a patient with ARDS, as well as ground-glass opacities in the non-dependent lung. A: Computed.
A: The Parker Flex-Tip tube (left) has a flexible tip pointing toward the center of the distal lumen. A: The Parker Flex-Tip tube (left) has a flexible.
Sensitivity, Specificity, Positive Predictive Value, Negative Predictive Value, Area Under the Curve, and 95% CIs for the 0, 10, 25, 50, and 100 SatSeconds.
Representative tracings of transcutaneous CO2 (PtcCO2), Spo2, and heart rate during an apnea test designed to raise Paco2 to 100 mm Hg. At baseline, PtcCO2.
Trigger and synchronization windows.
Whisker plot of expiratory pressure-time product: Direct comparison of expiratory pressure-time product (PTPEXP) in face mask versus helmet in all tested.
Typical pressure-time curves during forced expiration against an occluded airway in cystic fibrosis (CF) patients and healthy controls. Typical pressure-time.
Mean pulmonary arterial pressure (Ppa) as a function of cardiac output (Q) at two different levels of pulmonary vascular resistance (PVR). Mean pulmonary.
Bland-Altman plots of carbon dioxide elimination (V̇CO2) results in the adult range compared with the simulated values and with each other. Bland-Altman.
Serial chest x-rays of our patient.
Ineffective efforts and operation of apnea ventilation during pressure control continuous spontaneous ventilation (PC-CSV). Ineffective efforts and operation.
Example of Aerogen Solo Nebulizer before use with a fill volume of 3 mL normal saline (arrow 1) (A); the same nebulizer after random premature cessation.
Rebound Pulmonary Hypertension After Inhalation of Nitric Oxide
Negative pressures calculated with the Rosen and Hillard formula
A computed tomographic scan of the chest shows diffuse bilateral patchy pulmonary infiltrates predominant in the peripheries, with surrounding ground-glass.
We connected the supplemental oxygen supply at 3 places: near the ventilator, near the exhalation valve, and on the nasal mask port. We connected the supplemental.
Change in mean pulmonary arterial pressure after a 5-min inhalation of the Rho kinase inhibitor Y in rats with hypoxic pulmonary hypertension, with.
Three-dimensional computed tomogram reconstruction of the great vessels extending into the neck, documenting a pseudo-aneurysm of the right innominate.
Areas under the receiver operating characteristic (ROC) curves for both the training and testing data sets based on a number of hidden-layer perceptrons.
A: Optimal cutoff point (circled) at which visual analog scale score categorizes subjects with versus those without bronchial obstruction. A: Optimal cutoff.
The concept of using pulmonary function tests to place subjects into physiologic “buckets” using the interpretation algorithm of the American Thoracic.
A: Posteroanterior chest radiograph showing hypertranslucency of the left middle and lower fields with a marked reduction in the peripheral lung markings.
Comparison of alkaline glycine to normal saline inhalation (study 1).
Reduction in mean pulmonary vascular resistance (PVR) in 37 subjects following acute sildenafil administration to ongoing bosentan therapy in the COMPASS-1.
A: Pressure ulcer on the left cheek of a patient after 1 week of prone positioning using a commercially available endotracheal tube (ETT) holder. A: Pressure.
Kaplan-Meier curve for the probability of noninvasive ventilation (NIV) failure relative to continuous use of NIV and stratified for Acute Physiology and.
Mortality rate according to our integrated index that combines DH and exercise capacity. Mortality rate according to our integrated index that combines.
Total drug dose by device and condition while delivering 1 mL of ribavirin (5 min for the small-particle aerosol generator [SPAG] or 2 min for the vibrating.
SpO2 at baseline, pre- and post-intubation.
Calculated negative pressure developed in the lung plotted against the outside diameter of the suction catheter to the inside diameter of the airway. Calculated.
Survival of subjects listed for heart transplantation with and without spirometry. Survival of subjects listed for heart transplantation with and without.
Choosing inhaler therapy for patients with stable COPD based on the Global Initiative for Chronic Obstructive Lung Disease grouping. Choosing inhaler therapy.
Baseline New York Heart Association functional class (NYHA FC) predicts survival in patients with pulmonary hypertension using infused epoprostenol therapy.
PaO2/FIO2, leukocyte count, and C-reactive protein during the first 10 days after out-of-hospital cardiac arrest, in subjects with or without early-onset.
Ventilation protocol. Ventilation protocol. The PEEP group raised peak inspiratory pressure (PIP) through 5-cm H2O PEEP increments every 2 min while keeping.
Obstructive Sleep Apnea (OSA) may overlap with any number of pulmonary diseases, including COPD, cystic fibrosis (CF), etc. Obstructive Sleep Apnea (OSA)
A: Work of breathing before and after nebulized terbutaline delivered via standard nebulization method versus delivered during continuous positive airway.
Sequence plot visualizing the development of symptom frequency for the cohort at the individual level between 2006 and Sequence plot visualizing.
The changes in peak flow and inspiratory time between a minimum rise time (first 2 breaths) and a maximum rise time (last 2 breaths), with the Servo-i.
Representative tidal volume (VT) and breathing frequency (f) patterns of subjects with COPD and normal subjects during cardiopulmonary exercise testing.
Plot of the surface tension (γ) and area.
Experimental setup. Experimental setup. Each tested ventilator was connected to the TTL test lung via a ventilator circuit. An oxygen analyzer, a pressure.
Progression of spontaneous breathing trials administered during inspiratory muscle strength training study interventions. Progression of spontaneous breathing.
Efficiency of aerosol bronchodilator delivery during continuous high-flow system at different CPAP and flow levels. Efficiency of aerosol bronchodilator.
Lung model expiratory CO2 (or PETOv2) representing simulated alveolar CO2 at baseline (no high-flow nasal cannula) and effect on expiratory CO2 at different.
Relationship between the ΔP0. 1/end-tidal CO2 (ΔP0
A: Comparison of pediatric lung transplant survival between different age groups. A: Comparison of pediatric lung transplant survival between different.
Percent of extremely-low-birth-weight (ELBW) babies alive and off mechanical ventilation at 7 days, and median days on mechanical ventilation for ELBW.
A: On the first admission, chest radiograph revealed diffuse bilateral pulmonary infiltrations. A: On the first admission, chest radiograph revealed diffuse.
Cardiac index (CI) changes from baseline following single oral doses of riociguat (Rio) compared with inhaled nitric oxide (NO) in patients with chronic.
Arterial blood gas measurement of oxygen tension.
Effect of placebo (n=88) and bosentan (n=80) on the co-primary end-point pulmonary vascular resistance (PVR) in the EARLY (Endothelial Antagonist Trial.
Time taken to perform the Glittre activities of daily living (Glittre ADL) test by severity of COPD obstruction according to Global Initiative for Chronic.
Mean nasopharyngeal pressure during high-flow oxygen therapy, with mouth open or closed. Mean nasopharyngeal pressure during high-flow oxygen therapy,
Presentation transcript:

Pulmonary vascular resistance (PVR; dyn/s/cm) at baseline and after exposure to inhaled nitric oxide (INO; 20 ppm) for 10 min, inhaled epoprostenol (EPO; 50 μg/min) for 10 min, and the combination (Combo). * P < .05 versus baseline. Pulmonary vascular resistance (PVR; dyn/s/cm) at baseline and after exposure to inhaled nitric oxide (INO; 20 ppm) for 10 min, inhaled epoprostenol (EPO; 50 μg/min) for 10 min, and the combination (Combo). * P < .05 versus baseline. From Reference 7, with permission. Nicholas S Hill et al. Respir Care 2015;60:794-805 (c) 2012 by Daedalus Enterprises, Inc.