Volume 68, Issue 4, Pages (October 2005)

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Volume 68, Issue 4, Pages 1834-1839 (October 2005) BK virus nephritis: Risk factors, timing, and outcome in renal transplant recipients Brahm Vasudev, Sundaram Hariharan, Syed A. Hussain, Yong-Ran Zhu, Barbara A. Bresnahan, Eric P. Cohen Kidney International Volume 68, Issue 4, Pages 1834-1839 (October 2005) DOI: 10.1111/j.1523-1755.2005.00602.x Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 1 Life table graph showing actuarial renal transplant survival in all 41 cases with BKVN at our center. There is clear-cut reduction in graft survival in subjects with BKVN. Kidney International 2005 68, 1834-1839DOI: (10.1111/j.1523-1755.2005.00602.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 2 Comparison of the median decline in creatinine clearance for the four months before the diagnosis of BKVN and during subsequent follow-up after adjustment in immunosuppressive therapy in the 25 cases of group II. Kidney International 2005 68, 1834-1839DOI: (10.1111/j.1523-1755.2005.00602.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 3 (A) Time series plot of the evolution of renal function using 100/serum creatinine illustrating progressive renal failure in a case with BKVN in whom immunosuppression was unchanged. (B) Evolution of renal function using 100/serum creatinine illustrating stabilization of renal function in association with reduction in immunosuppressive therapy. Kidney International 2005 68, 1834-1839DOI: (10.1111/j.1523-1755.2005.00602.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 4 Overall and CNI immunosuppressive scale (IS) units at the time of diagnosis of BKVN and three months' postdiagnosis. The reduction in overall IS units did not correlate with slowing of the loss of renal function, but the reduction in CNI units did. Kidney International 2005 68, 1834-1839DOI: (10.1111/j.1523-1755.2005.00602.x) Copyright © 2005 International Society of Nephrology Terms and Conditions