Volume 5, Issue 7, Pages (July 2019)

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Volume 5, Issue 7, Pages (July 2019)

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Volume 5, Issue 7, Pages 617-620 (July 2019) Recurrent erythema multiforme major in an 8-year-old patient with recurrence of herpetic gingivostomatitis and HLA-B*5801 haplotype: A causal or casual relationship? Sara Grassi, MD, Grazia Bossi, MD, Giorgio A. Croci, MD, Valeria Brazzelli, MD JAAD Case Reports Volume 5, Issue 7, Pages 617-620 (July 2019) DOI: 10.1016/j.jdcr.2019.05.013 Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 An 8-year-old boy presents with abrupt onset of extensive sero-heamatic crusts covering his lips, associated with de-epithelialization of the oral mucosa and tongue (A). Blisters and ulcerations with perilesional erythema are evident on the upper limbs including palmar regions (B) and lower limbs (C). JAAD Case Reports 2019 5, 617-620DOI: (10.1016/j.jdcr.2019.05.013) Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Biopsy performed from perilesional skin of left leg is characterized by blistering at the dermoepidermal junction (black arrows), epidermal spongiosis, and keratinocytes apoptosis (red arrows). (A and B, Hematoxylin-eosin stain; original magnifications: A, ×20; B, ×40.) JAAD Case Reports 2019 5, 617-620DOI: (10.1016/j.jdcr.2019.05.013) Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions