The Stomach in Diabetes: From Villain to Ally

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The Stomach in Diabetes: From Villain to Ally Michael Camilleri  Clinical Gastroenterology and Hepatology  Volume 7, Issue 3, Pages 285-287 (March 2009) DOI: 10.1016/j.cgh.2008.10.031 Copyright © 2009 AGA Institute Terms and Conditions

Figure Regulation of glycemia in the postprandial period. Note that different nutrients stimulate release of a variety of hormones, some of which are involved in regulation of blood glucose. Several also affect gastric emptying including GIP, amylin, GLP-1, PYY, which ultimately inhibit vagal efferent function, resulting in inhibition of gastric emptying. Some of these hormones (eg, GIP, GLP-1) also stimulate β-cell mass and insulin secretion. AA, amino acid; CHO, carbohydrate; CCK, cholecystokinin; GIP, gastric inhibitory peptide; PYY, polypeptide YY. Clinical Gastroenterology and Hepatology 2009 7, 285-287DOI: (10.1016/j.cgh.2008.10.031) Copyright © 2009 AGA Institute Terms and Conditions