Detection of E-cadherin fragments in human prostate cancer metastases.

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Detection of E-cadherin fragments in human prostate cancer metastases. Detection of E-cadherin fragments in human prostate cancer metastases. A, liver metastasis (Liver Mets) from seven different patients and normal liver were analyzed for E-cadherin expression. B, different metastatic sites (Lanes 1 and 2, pelvic lymph node; Lane 3, brain; Lane 4, lung; Lane 5, adrenal gland; Lane 6, dural metastasis], derived from one autopsy case. Localized prostate cancer (Localized PCa) tissue used as negative control for 80 kDa expression. kDa, Mr in thousands. Rainer Kuefer et al. Clin Cancer Res 2003;9:6447-6452 ©2003 by American Association for Cancer Research