In Search of Human Hematopoietic Stem Cell Identity

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Presentation transcript:

In Search of Human Hematopoietic Stem Cell Identity Andrejs Ivanovs, Alexander Medvinsky Cell Stem Cell Volume 16, Issue 1, Pages 5-6 (January 2015) DOI: 10.1016/j.stem.2014.12.010 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Sequence of Appearance of HSCs during Human Development Prashad et al. (2014) identified GPI-80+ HSCs in the second trimester human fetal liver. The GPI-80 marker could be tracked back to cells in the first trimester human placenta, although the placenta at this stage does not contain HSCs (Ivanovs et al., 2011). It remains to be established whether GPI-80 marks the first HSCs in the human AGM region and can be used to follow their migration between different hematopoietic niches. CS, Carnegie stage. Cell Stem Cell 2015 16, 5-6DOI: (10.1016/j.stem.2014.12.010) Copyright © 2015 Elsevier Inc. Terms and Conditions