Fig. 3 Behaving like animals.

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Fig. 3 Behaving like animals. Behaving like animals. Here, we show similar clinical findings in veterinary and human patients with related naturally occurring diseases. Histologic photomicrographs (H&E) from a dog (A) and a human (a) with glioblastoma depict similar morphological features, including vascular proliferation. Close-up images of a dog (B) and a human (b) eye with KCS depict ocular surface changes. A computed tomographic three-dimensional reconstruction image of a dog (C) that received mandibular reconstruction using rh-BMP2 infused in a scaffold and a human (c) who has undergone mandibular reconstruction using autologous bone grafting. An echocardiogram from a cat (D) and a human (d) with hypertrophic cardiomyopathy demonstrates concentric hypertrophy of the left ventricle characterized by thickening of the left ventricular walls with decreased ventricular volume. A colonoscopic image from a dog (E) and a human (e) with inflammatory bowel disease demonstrates colonic inflammation, hemorrhage, and ulceration. A contrast-enhanced magnetic resonance myelogram in a dog (F) and a human (f) with cervical spondylomyelopathy depicts vertebral canal stenosis (white arrows). An arthroscopic image of a torn cranial cruciate ligament in a dog (G) and a torn anterior cruciate ligament in a knee of a human (g) reveals associated arthritic changes. Ultrasonographic images of a superficial digital flexor tendon lesion in a horse (H) and Achilles tendonitis in a human (h) demonstrate similar core lesions. Amir Kol et al., Sci Transl Med 2015;7:308ps21 Copyright © 2015, American Association for the Advancement of Science