Fig. 2 The increase in CD90+ mSSC abundance in fractured bones following local COX-2 overexpression depended on MCP-1. The increase in CD90+ mSSC abundance.

Slides:

Advertisements

Similar presentations

Fig. 5 Correlation of RNA expression and protein abundance.

Advertisements

Fig. 3 The electrical contact of direct-printed and reconfigured liquid metals. The electrical contact of direct-printed and reconfigured liquid metals.

Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,

Fig. 4 INS spectra of different human bones from the Roman period [humerus, ulna, femur, and fibula from the same skeleton, Guidonia-Montecelio, Italy.

Fig. 2 CFD results. CFD results. Results of CFD simulations in horizontal (left column) and vertical (right column) cross-sections. All models oriented.

Taxonomic representation and metabolic potential in metagenomes

Fig. 3 Vibrational spectra of human bones from the Copper Age (Scoglietto cave, Italy). Vibrational spectra of human bones from the Copper Age (Scoglietto.

Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)

Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.

Fig. 1 Map of water stress and shale plays.

Fig. 1 Examples of experimental stimuli and behavioral performance.

Fig. 3 Electron PSD in various regions.

Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.

HT synthesis of boronic acids using the building block approach

Fig. 6 Comparison of properties of water models.

Single-base validation using ligation-amplification method and qPCR

Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.

Fig. 2 Influence of the Roadmap Epigenomics Program on the field of epigenomics research. Influence of the Roadmap Epigenomics Program on the field of.

Fig. 2 Reference-fixing experiment, results.

Fig. 3 Swarm material properties.

Fig. 5 Conservation of m6A in mammals.

Fig. 3 Glucose- and structure-dependent insulin release.

Fig. 2 TRXSS data. TRXSS data. TRXSS data covering delay times from 10 ns to 10 ms for wild-type DmCry (A), for the DmCry(H378A) mutant (B), and for XlPho.

Fig. 3 Rotation experiment, setup.

Fig. 1 Product lifetime distributions for the eight industrial use sectors plotted as log-normal probability distribution functions (PDF). Product lifetime.

Fig. 5 Structural photocycle for DmCry.

FTIR-ATR spectra of Neolithic faunal bones (Mora Cavorso cave, Italy)

Fig. 6 SNP rs is a functional SNP in 22Rv1 cells.

Cyclooxygenase 2 augments osteoblastic but suppresses chondrocytic differentiation of CD90+ skeletal stem cells in fracture sites by Samiksha Wasnik, Ram.

Fig. 5 Blocking of WNT/β-catenin signaling pathway completely abolished COX-2 overexpression–mediated augmentation of CD90+ mSSC osteoblast differentiation.

Fig. 1 Distribution of total and fake news shares.

Fig. 1 Local COX-2 overexpression selectively increased the abundance and prolonged the presence of CD90+ mSSCs in the fractured bones. Local COX-2 overexpression.

Fig. 4 Reconstitution of MCs in KitW-sh/W-sh mice increases IL-10+ Breg cells and suppresses the CHS response. Reconstitution of MCs in KitW-sh/W-sh mice.

Fig. 2 2D QWs of different propagation lengths.

Fig. 6 Local COX-2 overexpression targeted CD90+ mSSCs to accelerate bone repair. Local COX-2 overexpression targeted CD90+ mSSCs to accelerate bone repair.

Fig. 1 Histograms of the number of first messages received by men and women in each of our four cities. Histograms of the number of first messages received.

Fig. 5 Schematic phase diagrams of Ising spin systems and Mott transition systems. Schematic phase diagrams of Ising spin systems and Mott transition systems.

Fig. 4 OER performance of ACoO3 (A = Ca, Sr) in alkaline solutions with different pH. OER performance of ACoO3 (A = Ca, Sr) in alkaline solutions with.

Fig. 5 Topology structure and strategy for the bottom-up synthesis of structurally uniform carboncones[1,m]. Topology structure and strategy for the bottom-up.

Fig. 1 Average contribution (million metric tons) of seafood-producing sectors, 2009–2014. Average contribution (million metric tons) of seafood-producing.

Fig. 4 The distribution of the target diagnoses in premutation carriers and controls for codes received before age 40. The distribution of the target diagnoses.

Fig. 4 Praying Prophet by Lorenzo Monaco: Mapping lake pigments and associated substrate. Praying Prophet by Lorenzo Monaco: Mapping lake pigments and.

Fig. 2 Magnetic properties of FGT/Pt bilayer.

Contrast agent uptake for the four different groups of MMA mice

Fig. 3 Production of protein and Fe(II) at the end of growth correlated with increasing concentrations of ferrihydrite in the media that contained 0.2.

Fig. 2 IRF8 is expressed in CD68+ macrophages after SCI.

Fig. 2 Schematic drawings of Göbekli Tepe skulls.

Fig. 1 Size fractions of MPPs in different fertilizers.

Fig. 4 Dox-CBD-SA treatment shows reduced toxicity.

Fig. 2 Viperin promotes methionine oxidation of KSHV helicase.

Fig. 5 Comparison of the liquid products generated from photocatalytic CO2 reduction reactions (CO2RR) and CO reduction reactions (CORR) on two catalysts.

Schematic of the proposed brain-controlled assistive hearing device

Fig. 1 Location of the Jirzankal Cemetery.

Fig. 4 CO2 emission changes triggered by the JJJ clean air policy.

Experimenter gender and replicability in science

AV3 potentiates the effect of gemcitabine in the PDX model in mice

Fig. 1 Schematic depiction of a paradigm for rapid and guided discovery of materials through iterative combination of ML with HiTp experimentation. Schematic.

Fig. 4 Mapping of abundance of the most dominant bacterial and archaeal phyla across France. Mapping of abundance of the most dominant bacterial and archaeal.

Fig. 4 Spatial mapping of the distribution and intensity of industrial fishing catch. Spatial mapping of the distribution and intensity of industrial fishing.

Fig. 3 Device architecture, photovoltaic performance, and operational stability of 3D/2D bilayer PSCs. Device architecture, photovoltaic performance, and.

Fig. 4 Single-particle contact angle measurements.

Fig. 5 Density plots showing the relationship between growth responses to extreme events and site-level mean precipitation from all sites (N = 1314). Density.

Fig. 3 Performance of the generative model G, with and without stack-augmented memory. Performance of the generative model G, with and without stack-augmented.

Fig. 4 Behavior of resistance peak near density nm = 5.

Fig. 2 Comparison between the different reflective metasurface proposals when θi = 0° and θr = 70°. Comparison between the different reflective metasurface.

Fig. 3 Calculated electronic structure of ZrCoBi.

Fig. 1 Attractive interaction between a doublon and a holon due to antiferromagnetic exchange interactions in half-filled 2D Mott insulators. Attractive.

Fig. 3 Evaluation of PTMAO immunogenicity.

Fig. 5 CD19-tPSMA(N9del) CAR T cell numbers in mouse and human.

Fig. 3 Temperature-dependent heat capacity of YbTM2Zn20.

Presentation transcript:

Fig. 2 The increase in CD90+ mSSC abundance in fractured bones following local COX-2 overexpression depended on MCP-1. The increase in CD90+ mSSC abundance in fractured bones following local COX-2 overexpression depended on MCP-1. (A) B6 mice received femur fracture surgery and treatments as described in Fig. 1. On day 4 following the treatments, the fractured bones and contralateral intact bones were harvested and analyzed by RT-qPCR. Data are shown in (B). (B) Data show the expression of MCP-1 mRNA. GAPDH, glyceraldehyde-3-phosphate dehydrogenase. (C) B6 mice received femur fracture surgery. Beginning on the day of fracture surgery, the mice subcutaneously received a daily dose of either PBS or the neutralizing anti–MCP-1 mAb (anti–MCP-1, clone 2H5) near the fracture sites for three consecutive days (±mAb). In addition, on the day following the fracture surgery, half of the animals from each group received a treatment of a control AAV vector and the other half the AAV.COX-2 vector in fracture sites. On day 4 following the treatments, the fractured bones and contralateral intact bones were harvested and the MNCs were isolated for analyses by FACS. Data are shown in (D) and (E). (D) Representative FACS plots show the expression of CD90 among mSSCs. (E) Cumulative data show the frequencies of CD90+ mSSCs in the fractured bones. Where applicable, data are means ± SEM. **P < 0.01, ***P < 0.001, ****P < 0.0001; n = 3 to 5. Samiksha Wasnik et al. Sci Adv 2019;5:eaaw2108 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).