Prasugrel and ticagrelor versus clopidogrel; risk ratio with 95% CIs for the primary composite end point of cardiovascular death, non-fatal myocardial infarction and non-fatal stroke. Prasugrel and ticagrelor versus clopidogrel; risk ratio with 95% CIs for the primary composite end point of cardiovascular death, non-fatal myocardial infarction and non-fatal stroke. Also, major bleeding in the diabetic populations managed with and without insulin; comparing prasugrel and ticagrelor versus clopidogrel in addition to aspirin. Event rate percentage of newer agent versus clopidogrel. DM, diabetes mellitus. Jennifer A Rossington et al. Open Heart 2016;3:e000296 ©2016 by British Cardiovascular Society