Antagonizing XIAP-mediated caspase-3 inhibition

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Antagonizing XIAP-mediated caspase-3 inhibition Yihua Huang, Miao Lu, Hao Wu Cancer Cell Volume 5, Issue 1, Pages 1-2 (January 2004) DOI: 10.1016/S1535-6108(03)00340-4

Figure 1 XIAP, caspases, and XIAP antagonists A: Domain organization of XIAP, showing the regions responsible for caspase-3/7 and caspase-9 inhibition. B: Differential caspase activation status in cancer and normal cells and effects of different XIAP antagonists, polyphenylureas, and Smac peptides. Cancer Cell 2004 5, 1-2DOI: (10.1016/S1535-6108(03)00340-4)