James Parkinson, Celine Charon, Barbara S. Baker, Anne V

Slides:

Advertisements

Similar presentations

The CXC Receptor 2 Is Overexpressed in Psoriatic Epidermis

Advertisements

Quantitative Real-Time Reverse Transcription–Polymerase Chain Reaction Analysis of Drug Metabolizing and Cytoprotective Genes in Psoriasis and Regulation.

Interleukin-10 Downregulates Anti-Microbial Peptide Expression in Atopic Dermatitis Michael D. Howell, Natalija Novak, Thomas Bieber, Saveria Pastore,

Role of Angiogenic and Inflammatory Signal Pathways in Psoriasis

Francesca Capon Journal of Investigative Dermatology

A New View of Vitiligo: Looking at Normal-Appearing Skin

Nehal N. Mehta, Pradeep K. Dagur, Shawn M. Rose, Haley B

Matthew O. Ivory, James C. Birchall, Vincent Piguet

Anne L. S. Chang, Gil Atzmon, Aviv Bergman, Samantha Brugmann, Scott X

Irwin Freedberg: Physician-Scientist and Mentor

Mechanisms of Action of Etanercept in Psoriasis

Interferon α-Inducible Protein 27 (IFI27) is Upregulated in Psoriatic Skin and Certain Epithelial Cancers Sari Suomela, Li Cao, Anne Bowcock, Ulpu Saarialho-Kere,

Kavitha K. Reddy Journal of Investigative Dermatology

Skin CD4+ T Cells Produce Interferon-γIn Vitro in Response to Streptococcal Antigens in Chronic Plaque Psoriasis Dean W. Brown, Barbara S. Baker, Jean-Marc.

The Complexity of Elastic Fiber Biogenesis: The Paradigm of Cutis Laxa

Photosensitizing Agents and the Risk of Non-Melanoma Skin Cancer: A Population- Based Case–Control Study Zaineb H. Makhzoumi, Sarah T. Arron Journal.

Irwin Freedberg, Odysseus for Our Generation

Presence of Epstein–Barr Virus in Langerhans Cells of CTCL Lesions

Differential Expression of Phosphorylated NF-κB/RelA in Normal and Psoriatic Epidermis and Downregulation of NF-κB in Response to Treatment with Etanercept

Interleukin-13 Receptor in Psoriatic Keratinocytes: Overexpression of the mRNA and Underexpression of the Protein Juan C. Cancino-Díaz, Elba Reyes-Maldonado,

Francois le Pelletier, Anne Janin Journal of Investigative Dermatology

Langerhans Cells Integrated into Human Reconstructed Epidermis Respond to Known Sensitizers and Ultraviolet Exposure Valérie Facy, Virginie Flouret,

High Levels of Ultraviolet B Exposure Increase the Risk of Non-Melanoma Skin Cancer in Psoralen and Ultraviolet A-Treated Patients Jean Lee Lim, Robert.

Increased Oxidative Damage to Fibroblasts in Skin With and Without Lesions in Psoriasis Stéphanie Dimon-Gadal, Pascale Gerbaud, Jean Guibourdenche, Danièle.

Caspase-5 Expression Is Upregulated in Lesional Psoriatic Skin

Clinical Snippets Journal of Investigative Dermatology

Minutes of the Board of Directors Meeting

Inflammatory Events Are Involved in Acne Lesion Initiation

Superantigens, Autoantigens, and Pathogenic T Cells in Psoriasis

Star Trek Publishing Journal of Investigative Dermatology

Mayte Suárez-Fariñas, Judilyn Fuentes-Duculan, Michelle A

Differential Expression of Cytokine mRNA in Skin Specimens from Patients with Erythema Migrans or Acrodermatitis Chronica Atrophicans Robert R. Müllegger,

High-Density Lipoprotein Cholesterol Function Improves after Successful Treatment of Psoriasis: A Step Forward in the Right Direction Nehal N. Mehta,

Manabu Taniguchi, Shinsuke Matsuzaki, Masaya Tohyama

Journal of Investigative Dermatology

Journal of Investigative Dermatology

CXCR4 in Epidermal Keratinocytes: Crosstalk within the Skin

Mitogen- and Stress-Activated Protein Kinase 2 and Cyclic AMP Response Element Binding Protein are Activated in Lesional Psoriatic Epidermis Anne T.

Transcriptional Profiling of Psoriasis Using RNA-seq Reveals Previously Unidentified Differentially Expressed Genes Ali Jabbari, Mayte Suárez-Fariñas,

Society for Investigative Dermatology 2010 Meeting Minutes

Maria T. García-Romero, Roberto Arenas

BJD Editor's Choice Journal of Investigative Dermatology

Presence of Chimeric Maternally Derived Keratinocytes in Cutaneous Inflammatory Diseases of Children: The Example of Pityriasis Lichenoides Kiarash Khosrotehrani,

Cells of Origin in Skin Cancer

The Viral Etiology of Skin Cancer

Research Snippets Journal of Investigative Dermatology

Journal of Investigative Dermatology

Genetic Influences on Human Body Odor: From Genes to the Axillae

Expression of Mast Cell Growth Modulating and Chemotactic Factors and their Receptors in Human Cutaneous Scars Barbara Hermes Journal of Investigative.

Metabolic Vulnerability in Melanoma: A ME2 (Me Too) Story

Research Snippets from the British Journal of Dermatology

Persistent Transgene Expression and Normal Differentiation of Immortalized Human Keratinocytes In Vivo Gerald G. Krueger, Cynthia M. Jorgensen, Andrew.

25 Years of Epidermal Stem Cell Research

Research Snippets Journal of Investigative Dermatology

Journal of Investigative Dermatology

Conceptual Issues in Measuring the Burden of Skin Diseases

Irwin Freedberg: The Early Years at Harvard

The Level of Prosaposin is Decreased in the Skin of Patients with Psoriasis Vulgaris Francesca Alessandrini, Silke Stachowitz, Johannes Ring, Heidrun.

Increased Serum CCL28 Levels in Patients with Atopic Dermatitis, Psoriasis Vulgaris and Bullous Pemphigoid Shinji Kagami, Takashi Kakinuma, Hidehisa.

Marie-Louise T. Johnson

Helen L. Richards, Dónal G. Fortune, Stephanie L. P. Chong, Damon L

Volume 24, Issue 3, Pages (March 2006)

Lack of Membrane Expression of Interleukin-2 Receptor α Chain (CD25) in Mycosis Fungoides: Application of Laser Scanning Cytometry for Phenotyping of.

Psoriasis Autoantigens in Normal Scalp Skin—Identification by Expression Cloning Eva Hagforsen, Karin Sunnerberg, Gerd Michaëlsson, Olle Kämpe, Håkan.

Psoriasis Genetics: The Way Forward

Journal of Investigative Dermatology

Journal of Investigative Dermatology

Journal of Investigative Dermatology

Redistribution of LRIG Proteins in Psoriasis

Induction of Matrix Metalloproteinase-9 in Keratinocytes by Histamine

Presentation transcript:

Variation at the IRF2 Gene and Susceptibility to Psoriasis in Chromosome 4q-Linked Families James Parkinson, Celine Charon, Barbara S. Baker, Anne V. Powles, Sarah Rogers, Ann Caird, Damian Smedley, Stephanie Halford, Lionel Fry, Mark I. McCarthy Journal of Investigative Dermatology Volume 122, Issue 3, Pages 640-643 (March 2004) DOI: 10.1046/j.0022-202X.2004.22135.x Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 IRF2 expression in skin biopsies. Keratinocyte IRF2 expression is unaltered in lesional skin form 4q-linked psoriasis patients. Immunostaining of normal (a), nonlesional psoriatic (b), 4q-linked lesional psoriatic (c), and lesional psoriatic skin of unknown linkage (d) using the avidin–biotin–peroxidase technique and polyclonal antibody specific for IRF2. e, epidermis; d, dermis. Scale bar=75 μm. Journal of Investigative Dermatology 2004 122, 640-643DOI: (10.1046/j.0022-202X.2004.22135.x) Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions