Nicolas Unsain, Philip A. Barker Neuron

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New Views on the Misconstrued: Executioner Caspases and Their Diverse Non- apoptotic Roles Nicolas Unsain, Philip A. Barker Neuron Volume 88, Issue 3, Pages 461-474 (November 2015) DOI: 10.1016/j.neuron.2015.08.029 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Sublethal Caspase Activation Regulates Several Aspects of Neuron Biology Neuronal activities in which sublethal caspase activity plays a significant role are indicated. Activities shown in blue text indicate caspase functions that represent normal physiological roles, and those in red indicate roles for sublethal caspase activity after injury or in disease. See text for details. Neuron 2015 88, 461-474DOI: (10.1016/j.neuron.2015.08.029) Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 2 Regulation of Sublethal Caspase Activity Schematic showing distinct pathways that have been implicated in caspase-9 activation in sublethal settings as well as negative regulatory elements that may facilitate or suppress sublethal caspase activation. See text for details. Neuron 2015 88, 461-474DOI: (10.1016/j.neuron.2015.08.029) Copyright © 2015 Elsevier Inc. Terms and Conditions