Figure 1. Main autopsy findings in a kidney transplant recipient with fatal YF. A, Liver with brown-yellowish cut ... Figure 1. Main autopsy findings in.

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Presentation transcript:

Figure 1. Main autopsy findings in a kidney transplant recipient with fatal YF. A, Liver with brown-yellowish cut ... Figure 1. Main autopsy findings in a kidney transplant recipient with fatal YF. A, Liver with brown-yellowish cut surface due to steatosis; B, Histological aspect of a severe YF hepatitis affecting the entire hepatic lobe, reaching the periportal area, with steatotic (thick arrows) and apoptotic (thin arrows) hepatocytes, Kupffer cell hyperplasia, and minimal inflammatory reaction; C, Immunohistochemistry reaction detecting YF virus antigens in the cytoplasm of steatotic and apoptotic hepatocytes (arrow). D, Pancreas with diffuse ischemic/reperfusion pancreatitis, with numerous hemorrhagic steatonecrosis spots (arrow). E, Coronal cut of brain showing diffuse perivascular microhemorrhages (arrow) in the white matter. Scale bars: 50 µm in B and C. Abbreviation: YF, yellow fever. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Clinical Infectious Diseases, ciz389, https://doi.org/10.1093/cid/ciz389 The content of this slide may be subject to copyright: please see the slide notes for details.