Acute Inflammation

Serofibrinous peritonitis neutrophils fibrin Liver Fibrin

Acute diffuse suppurative appendicitis Ulcerated mucosa Low power Swollen appendix intact mucosa Purulent exudate neutrophils Lymph follicle High power Ulcerated mucosa Ulcerated mucosa glands neutrophils

Lobar pneumonia Consolidated lobe

Lobar pneumonia pleura High power Low power fibrin Exudate in alveoli Interalveolar septae neutrophils

Chronic Inflammation & Repair

Chronic Inflammation Lymphocytes Blood vessels Plasma cells

Granulation Tissue capillaries Low power High power Capillary fibroblast

Myocardial scar scar myocardium scar Left ventricle scar myocardium

Intra & Extracellular deposits

Hyalinosis, Spleen Hyaline change In central arteriole Lymph Follicle(white Pulp)

Amyloidosis Kidney High power Low power Amyloid in glomeruli Amyloid in afferent arterioles

Amyloidosis , liver Amyloid material (pale pink) Liver cell cords

Fatty change , Liver(Steatosis) High power Low power Central vein Fat vacuole in liver cell vacuolated liver cells

Fatty change, liver(Steatosis) rounded border High power Vacuolated hepatocyte (signet ring appearance) Yellow cut section Portal tract

Brown atrophy ,heart Lipofuscin pigment

Disorders of Blood Flow

Chronic venous congestion, lung Low power High power anthracosis Heart failure cells Thickened interalveolar septae

Chronic venous congestion,liver Central vein Central vein Low power Central sinusoidal congestion and necrosis

Chronic venous congestion,liver High power Notice the similarity of the cut section of the liver to the cut section of the nutmeg (left) Congested central sinusoids Dark areas are congested sinusoids giving the cut section of liver a nutmeg appearance central vein

Recent Thrombus vessel thrombus Low power High power thrombus Vessel wall *In the picture on the right the blood vessel is opened longitudinally. The thrombus appears as red jelly- like material adherent to the intima. *The lines of Zahn represents the aplatelets, They appear purple in color. Lines of Zahn fibrin

Infarction, Spleen Recent infarctions Zone of hyperemia Coagulative necrosis (infarction) Splenic tissue Zone of acute inflammation

Infarction,Lung Infarction Lung showing chronic venous congestion Low Power High Power Hemorrhagic infarction