Acute Inflammation
Serofibrinous peritonitis neutrophils fibrin Liver Fibrin
Acute diffuse suppurative appendicitis Ulcerated mucosa Low power Swollen appendix intact mucosa Purulent exudate neutrophils Lymph follicle High power Ulcerated mucosa Ulcerated mucosa glands neutrophils
Lobar pneumonia Consolidated lobe
Lobar pneumonia pleura High power Low power fibrin Exudate in alveoli Interalveolar septae neutrophils
Chronic Inflammation & Repair
Chronic Inflammation Lymphocytes Blood vessels Plasma cells
Granulation Tissue capillaries Low power High power Capillary fibroblast
Myocardial scar scar myocardium scar Left ventricle scar myocardium
Intra & Extracellular deposits
Hyalinosis, Spleen Hyaline change In central arteriole Lymph Follicle(white Pulp)
Amyloidosis Kidney High power Low power Amyloid in glomeruli Amyloid in afferent arterioles
Amyloidosis , liver Amyloid material (pale pink) Liver cell cords
Fatty change , Liver(Steatosis) High power Low power Central vein Fat vacuole in liver cell vacuolated liver cells
Fatty change, liver(Steatosis) rounded border High power Vacuolated hepatocyte (signet ring appearance) Yellow cut section Portal tract
Brown atrophy ,heart Lipofuscin pigment
Disorders of Blood Flow
Chronic venous congestion, lung Low power High power anthracosis Heart failure cells Thickened interalveolar septae
Chronic venous congestion,liver Central vein Central vein Low power Central sinusoidal congestion and necrosis
Chronic venous congestion,liver High power Notice the similarity of the cut section of the liver to the cut section of the nutmeg (left) Congested central sinusoids Dark areas are congested sinusoids giving the cut section of liver a nutmeg appearance central vein
Recent Thrombus vessel thrombus Low power High power thrombus Vessel wall *In the picture on the right the blood vessel is opened longitudinally. The thrombus appears as red jelly- like material adherent to the intima. *The lines of Zahn represents the aplatelets, They appear purple in color. Lines of Zahn fibrin
Infarction, Spleen Recent infarctions Zone of hyperemia Coagulative necrosis (infarction) Splenic tissue Zone of acute inflammation
Infarction,Lung Infarction Lung showing chronic venous congestion Low Power High Power Hemorrhagic infarction