A simplified schematic representation of muscle wasting and weakness leading to decreased physical performance in patients with ESRD. In addition to specific.

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A simplified schematic representation of muscle wasting and weakness leading to decreased physical performance in patients with ESRD. In addition to specific issues noted in the diagram, decreased physical activity and sedentary lifestyle are major contribu... A simplified schematic representation of muscle wasting and weakness leading to decreased physical performance in patients with ESRD. In addition to specific issues noted in the diagram, decreased physical activity and sedentary lifestyle are major contributors to the muscle abnormalities that are observed in these patients. HPT, hyperparathyroidism; GH, growth hormone. T. Alp Ikizler, and Jonathan Himmelfarb JASN 2006;17:2097-2098 ©2006 by American Society of Nephrology