Fig. 4. Localization of nuclear factor I-C (Nfic), Phex, cytokeratin 14 (CK14), and Smo in the furcation region of developing mandibular first molar of Nfic knockout.

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Fig. 4. Localization of nuclear factor I-C (Nfic), Phex, cytokeratin 14 (CK14), and Smo in the furcation region of developing mandibular first molar of Nfic knockout mice at P14. (A, B) In wild type (WT) mice, Nfic was localized in odontoblasts and cells in the pulp and periodontium, whereas no immunoreactivity was observed in mutant (MT) mice. (C, D) Phex was localized in odontoblasts of both WT and MT mice. (E, F) CK14 was localized in the epithelial rests below the inter-radicular dentin dentin at the furcation region in both WT and MT mice. (G, H) Smo was localized in the odontoblasts and cells in the periodontium in WT mice. In MT mice, localization of Smo was found around Hertwig's epithelial root sheath (HERS). The black arrows indicate HERS. Ab, alveolar bone; P, pulp; Ird, inter-radicular dentin dentin at the furcation region; Od, odontoblasts. Scale bar=80 µm. Fig. 4. Localization of nuclear factor I-C (Nfic), Phex, cytokeratin 14 (CK14), and Smo in the furcation region of developing mandibular first molar of Nfic knockout mice at P14. (A, B) In wild type (WT) mice, Nfic was localized in odontoblasts and cells in the pulp and periodontium, whereas no immunoreactivity was observed in mutant (MT) mice. (C, D) Phex was localized . . . Anat Cell Biol. 2015 Sep;48(3):188-194. http://dx.doi.org/10.5115/acb.2015.48.3.188