Recombinants are produced by crossovers.

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Presentation transcript:

Recombinants are produced by crossovers.

Map distances are generally additive.

Longer regions have more crossovers and thus higher recombinant frequencies.

Independent assortment produces 50% recombinants.

For linked genes, recombinant frequencies are less than 50%.

Three Point Mapping: Forward Analysis Single Crossovers Region I (SCO I) jv se+ h+ jv+ se h 6.8 m.u. 0.5 m.u. jv se h jv+ se+ h+ Region: I II Single Crossovers Region II (SCO II) jv se h+ jv+ se+ h Double Crossovers (DCO) jv se+ h jv+ se h+ Prob(XO in Region I) = 0.068 Prob(XO in Region II) = 0.005 Prob(XOs in Region I and II) = No Crossovers, Parental (NCO) jv se h jv+ se+ h+ (0.068) x (0.005) = 0.00034

Three Point Mapping: Forward Analysis Prob(DCO) = (0.068) x (0.005) = 0.00034 Prob(SCO I) = 0.068 - 0.00034 = 0.06766 Prob(SCO II) = 0.005 - 0.00034 = 0.00466 Prob(NCO) = 1 - Prob(SCO I) - Prob(SCO II) - Prob(DCO) = 0.92734 6.8 m.u. 0.5 m.u. jv se h jv+ se+ h+ Region: I II Double Crossovers (DCO) jv se+ h jv+ se h+ Single Crossovers Region I (SCO I) jv se+ h+ jv+ se h Single Crossovers Region II (SCO II) jv se h+ jv+ se+ h No Crossovers, Parentals (NCO) jv se h jv+ se+ h+