Minimally invasive non-surgical locally injected vitamin C versus the conventional surgical depigmentation in treatment of gingival hyperpigmentation.

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Minimally invasive non-surgical locally injected vitamin C versus the conventional surgical depigmentation in treatment of gingival hyperpigmentation of the anterior esthetic zone: A prospective comparative study  Nermin M. Yussif, Ahmed R. Abdel Rahman, Ahmed ElBarbary  Clinical Nutrition Experimental  Volume 24, Pages 54-65 (April 2019) DOI: 10.1016/j.yclnex.2018.12.003 Copyright © 2019 The Authors Terms and Conditions

Fig. 1 The stages of vitamin C depigmentation; A: pre-operative, B: after 1st visit, C: after 2nd visit, D: after 3rd visit, E: after 1 month and F: after 9 months follow up. Clinical Nutrition Experimental 2019 24, 54-65DOI: (10.1016/j.yclnex.2018.12.003) Copyright © 2019 The Authors Terms and Conditions

Fig. 2 The red color represents the critical zone; the green color represents areas to be safely injected while the yellow color represents the areas to be injected with caution due to canine eminence (thin gingival and bone biotype). Clinical Nutrition Experimental 2019 24, 54-65DOI: (10.1016/j.yclnex.2018.12.003) Copyright © 2019 The Authors Terms and Conditions

Fig. 3 A) pre- and post-operative photos of vitamin C depigmentation, B) represents pre and post-operative photos of surgical depigmenation. Clinical Nutrition Experimental 2019 24, 54-65DOI: (10.1016/j.yclnex.2018.12.003) Copyright © 2019 The Authors Terms and Conditions

Fig. 4 Showing the mean values of changes in pigmentation in both groups according index 1. Clinical Nutrition Experimental 2019 24, 54-65DOI: (10.1016/j.yclnex.2018.12.003) Copyright © 2019 The Authors Terms and Conditions

Fig. 5 Showing the mean values of changes in pigmentation in both groups according index 2. Clinical Nutrition Experimental 2019 24, 54-65DOI: (10.1016/j.yclnex.2018.12.003) Copyright © 2019 The Authors Terms and Conditions

Fig. 6 Showing the mean values of changes in pain and itching in both groups. Clinical Nutrition Experimental 2019 24, 54-65DOI: (10.1016/j.yclnex.2018.12.003) Copyright © 2019 The Authors Terms and Conditions