Fig. 4 Modeled long-profile evolution.

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Fig. 4 Modeled long-profile evolution. Modeled long-profile evolution. Simulated Pleistocene evolution of the long profile of the upper Mississippi River. Light gray dashed lines indicate lithologic boundaries; shale is the most erodible and limestone and dolostone are the least erodible of those rock units encountered by the river. The pre-integration long profile was modified from our Pliocene surface to account for ~65 m of Pleistocene incision, calibrated to match the elevations of the Bridgeport Terrace in the Wisconsin River Valley (16) and the bedrock profile of the upper Mississippi south of St. Louis (Fig. 3). The incision model used a stream-power law with variable lithology and was forced by a GIA simulation based on the algorithm of (23) and the ICE-6G/VM5a ice-Earth model pairing (11) during the drainage reversal. pЄ, Precambrian (Midcontinent Rift) basement; ss, sandstone; ls&ds, limestone and dolostone. Andrew D. Wickert et al. Sci Adv 2019;5:eaav2366 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).