Fig. 1 Closed-loop artificial pancreas systems.

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New Developments in Insulin Therapy for Type 2 Diabetes
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Fig. 1 Closed-loop artificial pancreas systems. Closed-loop artificial pancreas systems. (A) Diagram depicting closed-loop insulin delivery. A continuous glucose monitor (CGM) worn subcutaneously transmits information about interstitial glucose concentrations to a smartphone or other control algorithm device (CAD), which hosts a control algorithm that translates information from the CGM and computes the amount of insulin to deliver. An insulin pump delivers rapid-acting insulin analog subcutaneously. Insulin delivery is modulated in real time by the control algorithm. Communication between system components is wireless. (B) Schematic depicting where the components of a closed-loop insulin delivery system may be worn and held by a human subject with type 1 diabetes. Charlotte K. Boughton and Roman Hovorka Sci Transl Med 2019;11:eaaw4949 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works