Survival among subjects with COPD, under age 65 and with similar pulmonary function impairment, in the Nocturnal Oxygen Therapy Trial (NOTT)58 and Intermittent.

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Presentation transcript:

Survival among subjects with COPD, under age 65 and with similar pulmonary function impairment, in the Nocturnal Oxygen Therapy Trial (NOTT)58 and Intermittent Positive Pressure Breathing (IPPB) studies.62 NOTT subjects (blue and black lines) had chronic hypoxemia and used oxygen either continuously (COT) or only at night (NOT); IPPB study subjects (green line) had the same severity of obstruction but were not hypoxemic and did not use oxygen. Survival among subjects with COPD, under age 65 and with similar pulmonary function impairment, in the Nocturnal Oxygen Therapy Trial (NOTT)58 and Intermittent Positive Pressure Breathing (IPPB) studies.62 NOTT subjects (blue and black lines) had chronic hypoxemia and used oxygen either continuously (COT) or only at night (NOT); IPPB study subjects (green line) had the same severity of obstruction but were not hypoxemic and did not use oxygen. Displaying the survival curves in this way supports Dr Petty's concept that, for any given severity of obstruction, continuous oxygen therapy restores the overall prognosis in hypoxemic COPD patients to what it would be if they were not hypoxemic. Data from Reference 62. David J Pierson Respir Care 2014;59:1287-1301 (c) 2012 by Daedalus Enterprises, Inc.