Interleukin (IL)-1β and IL-18 in stable chronic obstructive pulmonary disease (COPD) patients. a) IL-1β and IL-18 relative transcript levels in lung tissues.

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Interleukin (IL)-1β and IL-18 in stable chronic obstructive pulmonary disease (COPD) patients. a) IL-1β and IL-18 relative transcript levels in lung tissues of nonsmokers, smokers or COPD patients (relative quantification of mRNA levels relative to glyceral... Interleukin (IL)-1β and IL-18 in stable chronic obstructive pulmonary disease (COPD) patients. a) IL-1β and IL-18 relative transcript levels in lung tissues of nonsmokers, smokers or COPD patients (relative quantification of mRNA levels relative to glyceraldehyde 3-phosphate dehydrogenase). b) Spearman correlation of IL-1β mRNA expression levels in lungs of patients with stable COPD with forced expiratory volume in 1 s (FEV1 % reference). c) IL-1β and IL-18 protein levels measured by Luminex and ELISA, respectively, in lung tissue. a, c) Data is presented as mean±sem of n=14 nonsmokers, n=15 smokers and n=38 COPD individuals; b) each point represents an individual patient. **: p<0.01. Rosa Faner et al. ERJ Open Res 2016;2:00002-2016 ©2016 by European Respiratory Society